Cymbalta

duloxetine

Duloxetine Capsule: Effective Relief for Depression, Diabetic-Related Pain, and Fibromyalgia

What is Duloxetine?

Duloxetine is an antidepressant medication primarily prescribed to treat depression. Its effectiveness extends to managing pain resulting from diabetic complications and fibromyalgia.

Important Information

Before taking Duloxetine, inform your healthcare provider if you have any of the following conditions:

• Bipolar disorder or family history of bipolar disorder
• Kidney or liver disease
• Narrow-angle glaucoma
• Suicidal thoughts or previous suicide attempt
• Taken MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate within 14 days
• Unusual reaction to Duloxetine, other medications, foods, dyes, or preservatives
• Pregnancy or trying to conceive
• Breastfeeding

Dosage and Administration

• Take Duloxetine orally with a glass of water.
• Do not cut, crush, or chew the medication.
• It can be taken with or without food.
• Maintain regular intervals between doses.
• Avoid exceeding the prescribed dosage.
• Abrupt discontinuation after prolonged use may worsen symptoms. Gradually reduce the dose under medical supervision.
• Consult a pediatrician for appropriate dosage in children.
• In case of overdose, immediately contact a poison control center or emergency room.
• This medication is intended for individual use only.

Missed Dose

If you miss a dose, take it as soon as possible unless it's close to the time for the next dose. Avoid doubling up on doses.

Drug Interactions

Do not take Duloxetine with the following:

• Certain diet drugs like dexfenfluramine, fenfluramine, phentermine, sibutramine
• MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
• Procarbazine
• SSRIs like citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline
• St. John's Wort
• Thioridazine
• Tryptophan
• Venlafaxine

Duloxetine may also interact with the following:

• Aspirin and aspirin-like medications
• Certain antibiotics like ciprofloxacin and enoxacin
• Cimetidine
• Blood clot treatment medications like warfarin, enoxaparin, and dalteparin
• Heart rhythm or blood pressure medications
• NSAIDs for pain and inflammation like ibuprofen or naproxen
• Other medications for mental depression, mania, psychosis, or anxiety

This list is not exhaustive. Inform your healthcare providers about all medications, herbs, non-prescription drugs, or dietary supplements you use, including smoking, alcohol consumption, or illegal drug use. Certain substances may interact with Duloxetine.

Precautions

• Schedule regular check-ups with your healthcare provider.
• Continue taking your medication even if you don't feel immediate improvement. It may take up to 4 weeks to experience the full effect.
• Monitor yourself and your family for worsening depression or suicidal thoughts, sudden or severe changes in emotions, or unusual behavior.
• Drowsiness or dizziness may occur. Avoid driving, operating machinery, or engaging in activities requiring mental alertness until you understand how Duloxetine affects you. Stand or sit up slowly to minimize the risk of fainting spells.
• Avoid alcohol consumption as it may interfere with the medication's effectiveness.
• Consult your doctor before taking over-the-counter medications for coughs, colds, or allergies.
• Dry mouth is a potential side effect. Remedies include chewing sugarless gum, sucking hard candy, or drinking plenty of water.
• Duloxetine may cause an increase in blood pressure. Monitor your blood pressure and pulse as instructed by your healthcare provider.

Side Effects

Report the following side effects to your healthcare provider immediately:

• Allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• Changes in blood pressure
• Confusion
• Dizziness
• Fast talking and excited feelings or actions that are out of control
• Fast, irregular heartbeat
• Fever
• Hallucination, loss of contact with reality
• Seizures
• Stomach flu-like symptoms of diarrhea, vomiting
• Suicidal thoughts or other mood changes
• Unusual bleeding or bruising

Side effects that usually don't require medical attention (but should be reported if they persist or become bothersome):

• Blurred vision
• Change in appetite
• Change in sex drive or performance
• Headache
• Increased sweating
• Nausea

This list is not exhaustive.

Storage

• Keep out of reach of children.
• Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F).
• Discard any unused medication after the expiration date.

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Duloxetine Reviews

FAQs about Duloxetine

What is Duloxetine used for?

Duloxetine is primarily used to treat depression, diabetic nerve pain, and fibromyalgia pain.

How long does it take for Duloxetine to work?

It may take up to 4 weeks to experience the full effect of Duloxetine.

Can I drink alcohol while taking Duloxetine?

Alcohol may interfere with the effectiveness of Duloxetine. Avoid alcohol consumption while taking this medication.

What are the common side effects of Duloxetine?

Common side effects include nausea, headache, dry mouth, increased sweating, and dizziness.

Is Duloxetine safe to take long-term?

The safety of long-term Duloxetine use depends on individual factors and should be discussed with a healthcare provider.