Brand(s):
- Galvus
Manufacturer:
- Novartis
Disease(s):
- Diabetes / Type-2 Diabetes Mellitus
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Galvus
vidagliptin
Brand(s):
- Galvus
Manufacturer:
- Novartis
Disease(s):
- Diabetes / Type-2 Diabetes Mellitus
Vildagliptin tablets: Managing Type-2 Diabetes
What is Vildagliptin?
Vildagliptin is a medication prescribed for type-2 diabetes management. It contains the active compound vildagliptin and is available in 50 mg tablet form.
Therapeutic Uses of Vildagliptin:
- Monotherapy: For patients with uncontrolled diabetes who cannot tolerate or are contraindicated for metformin.
- Dual Therapy: Combined with metformin, a thiazolidinedione, a sulphonylurea, or insulin (with or without metformin) for enhanced glycemic control.
- Triple Therapy: Used in conjunction with a sulphonylurea and metformin when dual therapy fails to achieve satisfactory glycemic control.
How Does Vildagliptin Work?
Vildagliptin functions as a dipeptidyl-peptidase-4 (DPP-4) inhibitor. Its mechanism of action involves blocking the breakdown of incretin hormones, which are released after meals and stimulate insulin production. By elevating incretin levels, vildagliptin prompts the pancreas to secrete more insulin, thereby reducing blood sugar levels.
Dosage and Administration:
- Standard Dosage: One tablet twice daily (total 100 mg per day) for monotherapy or in combination with other antidiabetic medications.
- Reduced Dosage: One tablet once daily (50 mg per day) when combined with a sulphonylurea. Lower doses of sulphonylurea may be necessary to minimize the risk of hypoglycemia.
- Maximum Dosage: The daily dose should not exceed two tablets (100 mg).
- Patients with Moderate or Severe Kidney Issues: Recommended dosage is 50 mg once daily.
Side Effects of Vildagliptin:
The most commonly reported side effect of Vildagliptin is dizziness, occurring in 1 to 10 out of 100 patients. For a comprehensive list of potential side effects, refer to the patient information leaflet.
Contraindications:
Vildagliptin is contraindicated in individuals with known hypersensitivity to vildagliptin or any of its ingredients.
Precautions:
Liver function tests should be conducted prior to initiating Vildagliptin therapy and periodically throughout treatment, as it has been associated with liver problems.
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FAQs:
Q: How does Vildagliptin help manage type-2 diabetes?
A: Vildagliptin elevates incretin levels, stimulating the pancreas to release more insulin, leading to lower blood sugar.
Q: What are the potential side effects of Vildagliptin?
A: The most common side effect is dizziness, but a comprehensive list can be found in the patient information leaflet.
Q: How should Vildagliptin be taken?
A: Dosage varies depending on individual circumstances and should be prescribed by a healthcare provider.
Q: What precautions should be taken when using Vildagliptin?
A: Liver function tests are recommended before and during treatment.
User Reviews:
Alina K.
"Vildagliptin has been a game-changer in managing my diabetes. My blood sugar levels are much more stable now."
Rating: 4.5 out of 5
David M.
"I appreciate that Vildagliptin is a once-daily medication. It makes it easy to remember and has helped me stay on track with my diabetes management."
Rating: 4.8 out of 5
Sarah J.
"Vildagliptin has been a lifesaver. It has helped me control my diabetes without experiencing any major side effects."
Rating: 5 out of 5
