What is this medicine?

Solifenacin is a medication used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage). It works by relaxing the muscles of the bladder, reducing the need to urinate.

What should I tell my health care provider before I take this medicine?

Do not take Solifenacin if you are allergic to solifenacin, or have certain conditions.

• untreated or uncontrolled narrow-angle glaucoma
• a stomach disorder causing delayed emptying
• unable to urinate

Tell your doctor if you have any of these other conditions:

• Glaucoma
• Liver disease
• Kidney disease
• A blockage in your stomach or intestines
• History of Long QT syndrome.
• Pregnant or planning to become pregnant

How should I take this medicine?

Take Solifenacin exactly as prescribed by your doctor.

• Do not take in larger or smaller amounts or for longer than recommended.
• Follow the directions on your prescription label.
• Solifenacin is usually taken once per day.
• Take this medicine with water.
• Do not crush, chew, or break the tablet.
• Swallow it whole.
• Solifenacin can be taken with or without food.

What if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What should I watch for while taking this medicine?

Avoid becoming overheated or dehydrated during exercise and in hot weather.

Solifenacin can decrease perspiration and you may be more prone to heat stroke.

This medication may cause blurred vision and may impair your thinking or reactions.

Be careful if you drive or do anything that requires you to be alert and able to see clearly.

What side effects may I notice from this medicine?

Get emergency medical help if you have any of these signs of an allergic reaction to Solifenacin:

• hives
• difficulty breathing
• swelling of your face, lips, tongue, or throat

Stop using Solifenacin and call your doctor at once if you have a serious side effect such as:

• hot, dry skin and extreme thirst
• severe stomach pain, or constipation for 3 days or longer
• pain or burning when you urinate
• vision changes, eye pain, or seeing halos around lights
• urinating less than usual or not at all
• confusion, hallucinations
• high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling)
• severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling

Less serious Solifenacin side effects may include:

• headache, dizziness, drowsiness, feeling tired
• dry mouth, hoarse voice
• dry eyes, blurred vision
• nausea, loss of appetite, upset stomach, heartburn
• mild constipation
• fever, sore throat, body aches, or other flu symptoms

What may interact with this medicine?

Tell your doctor about all other medicines you use, especially:

• arsenic trioxide (Trisenox)
• carbamazepine (Carbatrol, Equetro, Tegretol)
• conivaptan (Vaprisol)
• nefazodone
• phenytoin (Dilantin)
• tacrolimus (Prograf)
• vandetanib (Caprelsa)
• antifungal medication such as itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), or voriconazole (Vfend)
• the hepatitis C medications boceprevir (Victrelis) or telaprevir (Incivek)
• HIV/AIDS medicine such as indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, Kaletra), or saquinavir (Invirase)
• an antibiotic such as azithromycin (Zithromax, Zmax, Z-Pack), clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), levofloxacin (Levaquin), moxifloxacin (Avelox), pentamidine (NebuPent, Pentam), rifampin (Rifadin, Rifater, Rifamate), or telithromycin (Ketek)
• an antidepressant such as amitriptylline (Elavil, Vanatrip, Limbitrol), citalopram (Celexa), clomipramine (Anafranil), or desipramine (Norpramin)
• anti-malaria medications such as chloroquine (Aralen), halofantrine (Halfan), or mefloquine (Lariam)
• heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), dronedarone (Multaq), flecainide (Tambocor), ibutilide (Corvert), procainamide (Procan, Pronestyl), propafenone (Rythmol), quinidine (Quin-G), or sotalol (Betapace)
• medicine to prevent or treat nausea and vomiting such as dolasetron (Anzemet), droperidol (Inapsine), or ondansetron (Zofran)
• medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), mesoridazine (Serentil), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon)
• migraine headache medicine such as sumatriptan (Imitrex, Treximet) or zolmitriptan (Zomig)
• narcotic medication such as methadone (Methadose, Diskets, Dolophine)

Where can I keep my medicine?

Store at room temperature away from moisture and heat.