Zyloprim

allopurinol

Brand(s):

• Zyric Swiloris

Manufacturer:

• Cipla Limited / Sun Pharmaceutical Industries Ltd.

Disease(s):

• Gout / Kidney Stones

Known as:

• Aloprim / Lopurin / Zyloprim

Allopurinol Tablets: Effectively Lowering Uric Acid Levels

What is Allopurinol?

Allopurinol is an enzyme blocker that combats elevated levels of uric acid in the body by reducing uric acid production. It is primarily used in treating gout and specific types of kidney stones.

How Does Allopurinol Work?

Allopurinol functions by inhibiting xanthine oxidase, an enzyme responsible for the conversion of hypoxanthine and xanthine to uric acid. This inhibition leads to decreased uric acid generation, thereby lowering uric acid levels.

Medical Uses of Allopurinol

• Gout: Allopurinol is effective in preventing gout attacks, reducing inflammation, and alleviating pain associated with gout.
• Kidney Stones: Allopurinol aids in the prevention of certain types of kidney stones, particularly those composed of uric acid.
• Cancer Treatment: In patients undergoing cancer chemotherapy, Allopurinol helps prevent high uric acid levels, which can result from the breakdown of cancer cells during therapy.

What Conditions Should I Inform My Doctor About Before Taking Allopurinol?

Before using Allopurinol, it's essential to inform your healthcare provider about any of the following conditions:

• Liver disease
• Kidney disease
• Diabetes
• Hypertension
• Unusual dietary habits (e.g., starvation diets)
• Allergies to Allopurinol or other medications, foods, dyes, or preservatives
• Pregnancy or plans for pregnancy
• Breastfeeding

Proper Dosage and Administration

• Take Allopurinol orally, typically once daily after a meal to minimize stomach upset. Follow your doctor's instructions for the exact dosage.
• Drink a full glass of water with each dose and at least 8 additional glasses (8 oz. each) throughout the day to prevent kidney stones.
• Your doctor may provide specific dietary guidance to decrease urine acidity (e.g., avoiding excessive amounts of ascorbic acid or Vitamin C).
• Dosage is determined based on your medical condition and response to therapy. Regular and consistent use is crucial for optimal benefits. Aim to take Allopurinol at the same time each day.

What Happens if I Miss a Dose?

If you miss a dose, take it as soon as you remember. However, if it's near the time for your next dose, skip the missed dose and resume your usual dosing schedule. Avoid doubling the dose to compensate for the missed one.

Potential Interactions with Other Medications

Contraindicated Medications:

• Didanosine

Potential Interactions:

• Certain antibiotics (amoxicillin, ampicillin)
• Certain asthma drugs (aminophylline, theophylline)
• Azathioprine
• 'Blood thinners' (e.g., warfarin)
• Chlorpropamide
• Cyclosporine
• Mercaptopurine
• Sulfinpyrazone
• 'Water pills' (e.g., thiazide diuretics such as hydrochlorothiazide)

Inform your healthcare provider about all medications you're taking, including prescription drugs, over-the-counter medications, nutritional supplements, and herbal products. Additionally, disclose any caffeine or alcohol consumption, smoking habits, or illegal drug use. These factors can impact the effectiveness or safety of Allopurinol therapy.

Warnings and Precautions

Drowsiness: Allopurinol may cause drowsiness. Exercise caution when engaging in activities requiring alertness, such as driving or operating machinery.

Alcohol Consumption: Limit alcohol intake while taking Allopurinol, as alcohol may reduce its effectiveness.

Pregnancy and Breastfeeding: Use Allopurinol during pregnancy only if clearly necessary and with careful consideration of the risks and benefits. Consult your doctor. Allopurinol passes into breast milk, so consult your doctor before breastfeeding.

Increased Gout Attacks: You may experience an increase in the frequency of gout attacks for several weeks or months after starting Allopurinol, as the body eliminates excess uric acid. Continue taking your prescribed medications for gouty attacks as directed by your doctor, as Allopurinol is not a pain reliever.

Possible Side Effects

Serious Side Effects (Report to Your Doctor or Healthcare Professional Immediately):

• Easy bleeding/bruising
• Signs of infection (e.g., fever, persistent sore throat)
• Change in the amount of urine
• Yellowing eyes or skin
• Severe stomach/abdominal pain
• Persistent nausea/vomiting/lack of appetite
• Dark urine
• Unusual tiredness
• Unusual weight loss

Common Side Effects (Usually Do Not Require Medical Attention, but Inform Your Doctor or Healthcare Professional if They Continue or Are Bothersome):

• Stomach upset
• Nausea
• Diarrhea
• Unusual taste
• Acute gouty attacks
• Drowsiness

Storage Conditions

Keep Allopurinol away from children and pets. Store at room temperature, between 59-77 degrees F (15-25 degrees C), in a dry place away from light and moisture. Avoid storing in the bathroom.

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Can I purchase Allopurinol with Bitcoin?

Yes, 24Med accepts Bitcoin and other cryptocurrencies as payment options.

Is Allopurinol available over-the-counter?

No, Allopurinol requires a prescription from a qualified healthcare provider.

What is the brand name for Allopurinol?

Allopurinol is available as a generic medication. Brand names may vary depending on the manufacturer.

How long does it take for Allopurinol to work?

It may take several weeks or months for Allopurinol to reach its full effect in reducing uric acid levels.

Can I take Allopurinol if I have liver or kidney disease?

Consult your healthcare provider for guidance on the appropriate dosage and precautions if you have liver or kidney disease.

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