Norvasc

amlodipine

Brand(s):

• Amlip Avacard

Manufacturer:

• Okasa Pharma Pvt. Ltd. / Ranbaxy Laboratories Ltd.

Disease(s):

• Hypertension / Angina

Known as:

• Amvaz / Norvasc

Amlodipine Tablet: A Comprehensive Guide

What is Amlodipine?

Amlodipine is a medication classified as a calcium-channel blocker. Its mechanism of action involves affecting the amount of calcium in your heart and muscle cells. This leads to the relaxation of blood vessels, thereby reducing the workload on your heart. Primarily, amlodipine is used to lower high blood pressure (hypertension) and alleviate various types of chest pain (angina). It's crucial to remember that amlodipine is not a cure for these conditions, but rather a treatment to manage symptoms.

Important Information to Share with Your Doctor Before Taking Amlodipine

Before starting amlodipine, it's essential to inform your healthcare provider about any pre-existing medical conditions, including:

• Heart problems such as heart failure or aortic stenosis
• Liver disease
• Low blood pressure (hypotension)
• Any known allergies to amlodipine, other medications, foods, dyes, or preservatives
• Pregnancy or plans to become pregnant
• Breastfeeding

Providing your doctor with a complete medical history is vital for safe and effective treatment.

How to Take Amlodipine

Amlodipine is administered orally. Simply swallow the tablet with a glass of water. It can be taken with or without food. Consistency is key; take your doses at regular intervals as prescribed by your doctor. Never exceed the recommended dosage. Discontinuing amlodipine should only be done under the guidance of your physician. Children and elderly patients (over 65) may require adjusted dosages; consult your doctor or pediatrician for appropriate guidance. In case of an overdose, immediately contact a poison control center or emergency room.

Remember: This medication is solely for your use. Do not share it with others.

What to Do If You Miss a Dose

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Never double up on doses to compensate for a missed one.

Potential Drug Interactions

Amlodipine can interact with various other medications, including (but not limited to):

• Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen
• Barbiturates such as phenobarbital
• Bosentan
• Herbal or dietary supplements (e.g., ginger, ginkgo biloba, ginseng, hawthorn, ma huang, melatonin, St. John's wort, red yeast rice)
• Imatinib (STI-571)
• Local or general anesthetics
• Antifungal medications (fluconazole, itraconazole, ketoconazole, voriconazole)
• Other high blood pressure medications
• HIV/AIDS medications
• Prostate medication
• Anticonvulsants (carbamazepine, phenobarbital, phenytoin, primidone, zonisamide)
• Monoamine oxidase inhibitors (MAOIs)
• Rifampin, rifapentine, or rifabutin
• Certain antibiotics (clarithromycin, erythromycin, telithromycin, troleandomycin)
• Certain heart rhythm medications (amiodarone, diltiazem, verapamil)
• Certain antidepressants (fluoxetine, fluvoxamine, nefazodone)
• Diuretics (water pills)
• Yohimbine
• Zafirlukast
• Zileuton

It is crucial to inform your doctor or healthcare professional about all medications you are taking, including over-the-counter drugs, supplements, and herbal remedies. This includes informing them about your caffeine, alcohol, smoking, and illicit drug use, as these can influence the effectiveness of amlodipine. Always consult your doctor before starting or stopping any medication.

Monitoring Your Health While Taking Amlodipine

Regularly monitor your blood pressure and pulse rate while taking amlodipine. Your doctor will advise you on the target values and when to seek medical attention. You may experience dizziness or lightheadedness. Avoid driving, operating machinery, or engaging in activities requiring alertness until you understand how amlodipine affects you. To minimize dizziness, avoid sudden changes in position (sitting or standing). Limit alcohol consumption, as it can exacerbate dizziness and increase flushing and rapid heartbeats. Never stop taking amlodipine abruptly; follow your doctor's instructions for gradual dose reduction. Inform your doctor if you are scheduled for surgery.

Possible Side Effects of Amlodipine

Side effects requiring immediate medical attention:

• Fainting spells, dizziness, or lightheadedness
• Irregular heartbeat, chest pain, palpitations
• Swelling of legs or ankles

Side effects that usually don't require medical attention (but should be reported if persistent or bothersome):

• Drowsiness
• Facial flushing
• Headache
• Nausea, vomiting
• Stomach pain or gas
• Weakness or fatigue

This list is not exhaustive. Other side effects may occur.

Storage Instructions

Keep amlodipine out of reach of children in a child-resistant container. Store at room temperature (15-30°C or 59-86°F), protected from light, and keep the container tightly closed. Discard any unused medication after the expiration date.