Zocor

simvastatin

Brand(s):

• Simlup Simlip Simvotin

Manufacturer:

• Lupin Limited / Okasa Pharma Pvt. Ltd. / Ranbaxy Laboratories Ltd.

Disease(s):

• Hypercholesterolemia / Heart Attack / Stroke / Angina / Blood Clots

Known as:

• Zocor

Simvastatin Tablet

What is Simvastatin?

Simvastatin is a medication classified as an HMG-CoA reductase inhibitor, commonly known as a "statin." Its primary function is to lower cholesterol and triglyceride levels in the blood. By reducing these fats, simvastatin can also help decrease the risk of heart attack, stroke, and other cardiovascular problems in individuals with risk factors for heart or blood vessel disease. It's generally recommended that simvastatin be used in conjunction with dietary and lifestyle modifications for optimal results.

Important Information for Your Doctor

Before starting simvastatin, it's crucial to inform your healthcare provider about the following:

• Regular alcohol consumption
• Kidney disease
• Liver disease
• Experiencing muscle aches or weakness
• Any other medical conditions
• Allergies to simvastatin, other medications, foods, dyes, or preservatives
• Pregnancy or plans to become pregnant
• Breastfeeding

How to Take Simvastatin

Simvastatin is taken orally with a glass of water. It can be taken with or without food. Maintain a consistent dosing schedule, following the prescribed instructions carefully. Avoid exceeding the recommended dosage.

Children require special consideration, so consult your pediatrician before administering simvastatin to a child.

In case of an overdose, immediately contact a poison control center or emergency room.

This medication is for personal use only; do not share it with others.

Missed Dose

If you miss a dose, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed dose and continue with your regular schedule. Never double the dose.

Potential Drug Interactions

Simvastatin should not be taken with the following medications:

• Antifungal medications such as itraconazole and ketoconazole
• Nefazodone
• Other cholesterol-lowering medications
• Red yeast rice
• Certain antibiotics, including clarithromycin, erythromycin, and telithromycin
• Some HIV medications like amprenavir, indinavir, and ritonavir

Simvastatin may also interact with:

• Alcohol
• Amiodarone
• Cyclosporine
• Danazol
• Diltiazem
• Grapefruit juice
• Fluconazole
• Verapamil
• Voriconazole
• Warfarin

This is not an exhaustive list of potential interactions. Always provide your healthcare provider with a complete list of all medications, herbal remedies, over-the-counter drugs, and dietary supplements you are taking. Also disclose any alcohol, tobacco, or illicit drug use, as these substances can affect the efficacy and safety of simvastatin.

Monitoring Your Health While on Simvastatin

Regular check-ups with your doctor are essential to monitor your progress and ensure your liver function remains healthy. You may undergo periodic blood tests to assess liver health.

Report any unexplained muscle pain, tenderness, or weakness, especially if accompanied by fever or fatigue, to your doctor immediately.

Simvastatin is only one component of a comprehensive heart-health program. Your doctor or a registered dietitian can provide guidance on a heart-healthy diet low in cholesterol and fat. It's crucial to limit alcohol consumption, avoid smoking, and maintain a regular exercise routine.

Simvastatin is contraindicated during pregnancy and breastfeeding due to the potential for serious adverse effects on the unborn child or infant. Consult your doctor or pharmacist for more information.

Inform your healthcare provider that you are taking simvastatin before undergoing any surgical procedure.

Certain antibiotics and antifungals may increase the risk of simvastatin side effects. Your doctor might temporarily discontinue simvastatin if you are prescribed these medications. Always seek professional advice before making any changes to your medication regimen.

Potential Side Effects

Side effects requiring immediate medical attention:

• Allergic reactions (skin rash, itching, hives, facial swelling)
• Dark urine
• Fever
• Joint pain
• Muscle cramps or pain
• Skin reactions (redness, blistering, peeling)
• Changes in urination
• Unusual fatigue or weakness
• Jaundice (yellowing of the eyes or skin)

Side effects that usually don't require medical attention (but inform your doctor if they persist or worsen):

• Constipation
• Heartburn
• Gastrointestinal upset

This list may not encompass all possible side effects.

Storage of Simvastatin

Keep out of reach of children. Store at room temperature below 30°C (86°F). Keep the container tightly closed. Discard any unused medication after the expiration date.