Avalide

irbesartan hydrochlorothiazide

Brand(s):

• Irovel

Manufacturer:

• Sun Pharmaceutical Industries Ltd.

Disease(s):

• Hypertension

Known as:

• Avalide

Irbesartan and Hydrochlorothiazide Tablets

What is Irbesartan and Hydrochlorothiazide?

Irbesartan and Hydrochlorothiazide is a combination medication. It contains irbesartan, which relaxes blood vessels, and hydrochlorothiazide, a diuretic (water pill) that helps your body get rid of excess salt and water. This combination is primarily used to treat high blood pressure (hypertension).

Important Information for Your Healthcare Provider

Before starting this medication, it's crucial to inform your doctor or healthcare provider about the following:

• Kidney disease: Irbesartan and Hydrochlorothiazide can affect kidney function, and your dosage may need adjustment.
• Liver disease: Your doctor needs to assess your liver health before prescribing this medication because it can affect how your body processes the medication.
• Low blood pressure (hypotension): This medicine may further lower your blood pressure, which can be problematic for people already experiencing low blood pressure.
• Dehydration: Dehydration can worsen the effects of this medicine and must be avoided.
• Heart disease: This medication can affect heart function, so make sure to inform your physician about your heart health.
• Diabetes: This medication may influence your blood sugar levels, potentially requiring adjustments to your diabetes treatment plan.
• Gout: Hydrochlorothiazide can increase uric acid levels which might worsen gout.
• Allergies: Any allergies to irbesartan, hydrochlorothiazide, sulfa drugs, or other medications, foods, dyes, or preservatives must be disclosed.
• Pregnancy or breastfeeding: This medication is not recommended during pregnancy, especially during the second or third trimester, and should be avoided while breastfeeding.
• Dietary restrictions: Your doctor should know about any special diets you follow, such as low-sodium diets.
• Other medical conditions: Any other health conditions, including autoimmune diseases like lupus, should be mentioned.
• Other medications: A complete list of all medications, including over-the-counter drugs, herbal remedies, and supplements, must be provided.

How to Take Irbesartan and Hydrochlorothiazide

This medication is taken orally with a glass of water. It can be taken with or without food. Follow your doctor's instructions carefully regarding dosage and frequency. Never adjust the dosage yourself; consult your doctor before making any changes.

Children: Consult your pediatrician before giving this medicine to a child. Special care and dosage adjustments may be necessary.

Missed Dose: If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Never double the dose.

Overdose: In case of an overdose, contact a poison control center or emergency room immediately.

This medication is for your personal use only. Do not share it with others.

Potential Drug Interactions

Irbesartan and Hydrochlorothiazide can interact with several other medications. It's crucial to inform your doctor about all medications you're taking, including:

• Barbiturates (e.g., phenobarbital)
• Corticosteroids (e.g., prednisone)
• Diabetes medications
• Other diuretics (e.g., triamterene, spironolactone, amiloride)
• Lithium
• NSAIDs (e.g., ibuprofen)
• Potassium salts or supplements
• Prescription pain medications
• Skeletal muscle relaxants (e.g., tubocurarine)
• Some cholesterol-lowering medications (e.g., cholestyramine, colestipol)

This is not an exhaustive list. Always provide your healthcare provider with a complete list of all medications and supplements you are using.

Monitoring Your Health While Taking Irbesartan and Hydrochlorothiazide

Regular checkups with your doctor are essential while taking this medication. Monitor your blood pressure regularly and keep a record of the readings to share with your doctor. Your doctor will guide you on the desired blood pressure levels and when to contact them.

Hydration: Stay well-hydrated; consult your doctor about your daily fluid intake. Report any severe diarrhea, vomiting, or excessive sweating immediately, as these can lead to dehydration.

Sun Sensitivity: This medication may increase your sensitivity to the sun. Use sunscreen, protective clothing, and limit sun exposure.

Drowsiness and Dizziness: Avoid driving, operating machinery, or engaging in activities requiring alertness if you experience drowsiness or dizziness. Avoid alcohol, which can exacerbate these side effects.

Other Precautions: Avoid self-treating coughs, colds, or pain without consulting your doctor, as some over-the-counter medications can interact with Irbesartan and Hydrochlorothiazide. Avoid salt substitutes unless advised otherwise by your doctor.

Possible Side Effects

Report to your doctor immediately if you experience:

• Allergic reactions (rash, itching, hives, swelling of the face, lips, or tongue)
• Breathing problems
• Dark urine
• Fast or irregular heartbeat, palpitations, or chest pain
• Feeling faint or lightheaded
• Muscle cramps
• Persistent dry cough
• Skin reactions (redness, blistering, peeling)
• Stomach pain
• Changes in urination
• Unusual bleeding or bruising
• Worsened gout pain
• Yellowing of the eyes or skin (jaundice)

Side effects that usually don't require immediate medical attention (but should be reported to your doctor if they persist or bother you):

• Changes in sex drive or performance
• Headache

This is not a complete list of all possible side effects.

Storage

Keep out of the reach of children. Store at room temperature between 15 and 30 degrees Celsius (59 and 86 degrees Fahrenheit). Discard any unused medication after the expiration date.