Inspra

eplerenone

Brand(s):

• Planep

Manufacturer:

• Lupin Limited

Disease(s):

• Heart Failure / Heart Attack / High Blood Pressure / Hypertension

Eplerenone Tablets

What is Eplerenone?

Eplerenone is a medication that works by blocking the effects of aldosterone, a hormone that plays a crucial role in regulating blood pressure. By interfering with aldosterone's action, eplerenone helps to control blood pressure and fluid balance in the body. It's primarily used to treat two key conditions:

• Congestive heart failure (CHF) following a heart attack: Eplerenone can help reduce the risk of death and hospitalization in patients who have experienced a heart attack and are suffering from CHF.

• High blood pressure (hypertension): Eplerenone can be used alone or in combination with other medications to effectively lower blood pressure and reduce the risk of associated complications.

It's important to note that eplerenone may also be prescribed for other conditions, as determined by a doctor.

Important Considerations Before Taking Eplerenone

Before starting eplerenone, it's vital to inform your doctor about your medical history. Eplerenone may not be suitable for everyone. You should not take this medicine if you:

• Are allergic to eplerenone or any of its ingredients.

• Have high potassium levels in your blood (hyperkalemia).

• Have severe kidney disease.

• Have type 2 diabetes with protein in your urine (this indicates kidney damage).

Furthermore, eplerenone can interact with other medications. It's crucial to disclose all medications you are currently taking, including over-the-counter drugs, herbal remedies, and supplements. This includes, but is not limited to:

• Nefazodone

• Verapamil

• Diuretics (water pills) such as amiloride, spironolactone, and triamterene

• Certain antibiotics like clarithromycin, erythromycin, and telithromycin

• Antifungal medications such as itraconazole and ketoconazole

• Hepatitis C medications like boceprevir and telaprevir

• HIV/AIDS medications such as nelfinavir and ritonavir

Additionally, let your doctor know if you have:

• Kidney disease

• Liver disease

• High cholesterol or triglycerides

• Are taking other heart or blood pressure medications (e.g., ACE inhibitors, ARBs).

Eplerenone is categorized as FDA pregnancy category B, meaning it's not expected to harm a developing fetus. However, discuss your pregnancy plans with your doctor. It's unknown if eplerenone passes into breast milk, so breastfeeding is generally discouraged while using this medication.

How to Use Eplerenone

Always follow your doctor's instructions and the prescription label carefully. The dosage may be adjusted to optimize your treatment. Never alter the dosage without consulting your doctor. Eplerenone can be taken with or without food. Regular blood tests and blood pressure monitoring are usually necessary while taking this medication. If you are using eplerenone for high blood pressure, continue taking it even if you feel well, as high blood pressure often has no noticeable symptoms. Long-term use may be required.

Missed Dose

If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. Never double up on doses.

Drug Interactions

Eplerenone can interact with numerous other medications, including over-the-counter drugs and supplements. Always inform your doctor and pharmacist about all medications you are taking to avoid potential interactions.

Possible Side Effects

Seek immediate medical attention if you experience any signs of an allergic reaction, such as hives, severe stomach pain, difficulty breathing, or swelling of the face, lips, tongue, or throat.

Contact your doctor promptly if you notice:

• Mood changes, vomiting, or reduced urination

• Swelling or rapid weight gain

• Signs of high potassium (slow heart rate, weak pulse, muscle weakness, tingling)

• Signs of low potassium (confusion, irregular heart rate, excessive thirst, increased urination, leg discomfort, muscle weakness)

Common side effects might include diarrhea, cough, dizziness, fatigue, and flu-like symptoms. This is not an exhaustive list, and other side effects are possible.

Storage

Store eplerenone at room temperature, away from moisture, heat, and light.