Namzaric

donezepil and memantine

Brand(s):

• Donecept M

Manufacturer:

• Cipla Pharmaceuticals Ltd.

Disease(s):

• Dementia Of The Alzheimer's Type

Donepezil and Memantine Tablets

What is this medication?

Donepezil and memantine tablets are a combination medication used to treat moderate to severe Alzheimer's disease dementia. Donepezil works by boosting the levels of acetylcholine, a neurotransmitter crucial for memory, thinking, and reasoning. People with Alzheimer's often have lower levels of this important chemical. Memantine, on the other hand, modulates the effects of another brain chemical, glutamate, that can contribute to the symptoms of Alzheimer's.

This medication is designed to help manage the symptoms of Alzheimer's, improving cognitive function and daily living abilities. It's important to understand that donepezil and memantine tablets are not a cure for Alzheimer's disease. The disease will continue to progress over time, even with treatment.

Important Information to Share with Your Healthcare Provider

Before starting this medication, it's crucial to inform your doctor about your complete medical history. This medication is not suitable for everyone. You should not take this medication if you have a known allergy to donepezil or memantine.

It's vital that your doctor knows if you have any of the following conditions:

• Asthma or other respiratory problems

• Heart disease or any heart rhythm irregularities

• A history of seizures

• A history of stomach ulcers or gastrointestinal bleeding

• Bladder obstruction or urinary problems

• Liver disease

• Kidney disease

Pregnant or breastfeeding women should discuss the risks and benefits of this medication with their doctor before use. The effects of donepezil and memantine on unborn and nursing babies are not fully understood.

How to Use This Medication

Always follow your doctor's instructions precisely when taking this medication. Never adjust the dosage on your own. The usual recommendation is to take the medication at bedtime, unless your physician advises otherwise. It can be taken with or without food.

If you require surgery or any dental procedure, inform your dentist or surgeon that you are taking donepezil and memantine. Temporary discontinuation of the medication may be necessary.

Never abruptly stop taking this medication. Sudden cessation can worsen your condition. Follow your doctor's instructions for gradually reducing the dosage if you need to discontinue treatment.

Store the medication at room temperature, away from direct sunlight, heat, and moisture.

Potential Drug Interactions

Numerous medications, including over-the-counter drugs, supplements, and herbal remedies, can interact with donepezil and memantine. It is essential to provide your doctor and pharmacist with a complete list of all medications, vitamins, and supplements you are currently taking, as well as any new medications you begin or stop taking.

Possible Side Effects

Seek immediate medical attention if you experience any signs of an allergic reaction, such as hives, difficulty breathing, or swelling of your face, lips, tongue, or throat.

Contact your doctor immediately if you experience any of the following:

• Persistent or severe vomiting

• Lightheadedness or fainting

• Slow heart rate

• Seizures

• Painful or difficult urination

• New or worsening breathing problems

• Signs of stomach bleeding (severe heartburn or stomach pain, bloody or black stools, coughing up blood, or vomit that resembles coffee grounds)

Common side effects can include:

• Nausea, vomiting, diarrhea, loss of appetite

• Headache

• Dizziness

• Easy bruising

This is not an exhaustive list of potential side effects. Consult your doctor or pharmacist if you experience any unusual or concerning symptoms.

Monitoring Your Condition

Always follow your doctor's advice regarding any dietary restrictions, fluid intake limitations, or activity modifications necessary while taking this medication. Regular check-ups are essential to monitor your progress and adjust the treatment plan as needed.