Zestoretic

lisinopril-hctz

Brand(s):

• Listril Plus

Manufacturer:

• Torrent Pharmaceuticals Limited

Disease(s):

• Hypertension

Known as:

• Prinzide / Zestoretic

Lisinopril and Hydrochlorothiazide Tablet

What is Lisinopril and Hydrochlorothiazide?

Lisinopril and Hydrochlorothiazide is a combination medication containing a diuretic (water pill) and an ACE inhibitor. It's primarily used to treat high blood pressure (hypertension). The diuretic component, hydrochlorothiazide, helps your body get rid of excess sodium and water, lowering blood volume and pressure. Lisinopril, an ACE inhibitor, works by relaxing blood vessels, further reducing blood pressure. This combined action makes it effective in managing hypertension.

Important Information to Share with Your Doctor

Before starting Lisinopril and Hydrochlorothiazide, it's crucial to inform your doctor about your complete medical history. This includes, but isn't limited to:

• Pre-existing conditions: Bone marrow disease, decreased urine production, heart or blood vessel disease, kidney disease, liver disease, lupus (an autoimmune disease), previous angioedema (swelling of the face, lips, or tongue), recent heart attack or stroke.
• Dietary restrictions: If you are following a special diet, such as a low-sodium diet.
• Allergies: Any allergies to lisinopril, hydrochlorothiazide, sulfa drugs, other medications, foods, dyes, or preservatives.
• Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or are breastfeeding.

How to Take Lisinopril and Hydrochlorothiazide

Take this medication exactly as prescribed by your doctor. Typically, it's taken orally with a glass of water. You can take it with or without food. Maintain a consistent dosing schedule. Never adjust the dosage or stop taking the medication without consulting your doctor. Children require special consideration; discuss its use with your pediatrician.

Overdosage: In case of an overdose, immediately contact a poison control center or emergency room.

What Happens If I Miss a Dose?

If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.

Potential Drug Interactions

Lisinopril and Hydrochlorothiazide can interact with several other medications. It is vital to provide your doctor with a comprehensive list of all medications, including over-the-counter drugs, herbal supplements, and vitamins you are taking. Some notable interactions include:

• Other blood pressure medications
• Diuretics (especially triamterene, spironolactone, or amiloride)
• NSAIDs (like ibuprofen)
• Potassium supplements or salt substitutes
• Lithium
• Diabetic medications
• Certain cholesterol-lowering medications (cholestyramine or colestipol)
• Corticosteroids (like prednisone)
• Barbiturates (like phenobarbital)
• Prescription pain medications
• Skeletal muscle relaxants (like tubocurarine)

Things to Watch For While Taking This Medicine

Regular check-ups with your doctor are essential to monitor your progress and blood pressure. Report any irregularities in your heartbeat immediately. Maintain adequate hydration; consult your doctor regarding your daily fluid intake, particularly if you experience severe diarrhea, vomiting, or excessive sweating. Dehydration can pose serious risks while taking this medication.

Women should discuss pregnancy plans with their doctor, as this medication can have serious side effects on an unborn child.

Drowsiness and dizziness are possible side effects. Avoid driving, operating machinery, or engaging in activities requiring alertness until you know how the medication affects you. Avoid sudden changes in posture to prevent dizziness or fainting. Alcohol can exacerbate these effects; limit alcohol consumption.

This medication may impact blood sugar levels. Diabetics should consult their doctor before adjusting their diabetic medications. Avoid salt substitutes unless advised otherwise by your doctor.

Increased sun sensitivity is possible. Use sunscreen and protective clothing when exposed to the sun. Avoid tanning beds and sun lamps.

Do not self-treat coughs, colds, or pain while taking Lisinopril and Hydrochlorothiazide without consulting your doctor. Some over-the-counter medications can raise blood pressure.

Possible Side Effects

Side effects requiring immediate medical attention:

• Confusion, dizziness, lightheadedness, or fainting
• Decreased urine production
• Difficulty breathing or swallowing, hoarseness, or throat tightness
• Fast or irregular heartbeat, palpitations, or chest pain
• Muscle cramps
• Nausea and vomiting
• Persistent dry cough
• Skin reactions (redness, blistering, peeling)
• Stomach pain
• Swelling of face, lips, tongue, hands, or feet
• Unusual rash, bleeding, bruising, or pinpoint red spots
• Worsened gout pain
• Yellowing of eyes or skin (jaundice)

Side effects that usually don't require immediate medical attention (but report to your doctor if they persist or bother you):

• Cough
• Decreased sexual function or desire
• Headache

Storage Instructions

Keep out of the reach of children. Store at room temperature (68-77°F or 20-25°C). Protect from moisture and excessive light. Keep the container tightly closed. Discard any unused medication after the expiration date.