Creon

pancrelipase

Brand(s):

• Panstal

Manufacturer:

• Cipla Limited

Disease(s):

• Lack Of Enzymes / Cystic Fibrosis / Chronic Inflammation Of The Pancreas / Blockage Of The Pancreatic Ducts

Known as:

• Creon / Pancrecarb / Pertzye / Ultrase / Viokase / Zenpep

Pancrelipase Capsules

What is Pancrelipase?

Pancrelipase is a medication containing a blend of three crucial enzymes: lipase, protease, and amylase. These enzymes are naturally produced by the pancreas and play a vital role in the digestion of fats, proteins, and carbohydrates. When the pancreas doesn't produce sufficient enzymes, Pancrelipase steps in to help.

Various health conditions can lead to enzyme deficiencies, including:

• Cystic fibrosis
• Chronic pancreatitis (inflammation of the pancreas)
• Pancreatic duct blockage
• Post-pancreatic surgery

Pancrelipase helps restore proper digestive function by supplementing these missing enzymes. It's important to remember that Pancrelipase is a replacement therapy; it doesn't address the underlying cause of the enzyme deficiency.

Important Information for Your Doctor

Before starting Pancrelipase, it's crucial to inform your doctor about certain factors. You should not take this medication if you:

• Have an allergy to pork proteins (as Pancrelipase often uses porcine-derived enzymes).
• Experience a sudden onset of pancreatitis or a worsening of existing pancreatic issues.

Additionally, let your doctor know if you have any of the following conditions, as they might affect how Pancrelipase works or its safety:

• Kidney disease
• Gout
• History of intestinal blockage

How to Take Pancrelipase

Always follow your doctor's prescription instructions precisely. Never alter the dosage or duration of treatment without consulting your physician. Here are some general guidelines:

• Take Pancrelipase with meals or snacks to optimize its effectiveness.
• Swallow the capsules with a full glass of water or juice.
• Avoid holding the capsules or their contents in your mouth, as this can cause irritation.
• Do not crush, chew, break, or open delayed-release or extended-release capsules. Swallow them whole.
• For easier swallowing, you may open regular capsules and sprinkle the contents onto a spoonful of soft food like applesauce or pudding. Swallow immediately; do not store for later use.
• Avoid inhaling the powder or letting it contact your skin, as it can cause irritation.
• Take Pancrelipase regularly as prescribed for consistent benefit.

Potential Drug Interactions

Pancrelipase can interact with other medications, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Always inform your doctor and pharmacist of all medications you are currently taking, have recently taken, or plan to take.

Monitoring Your Health While Taking Pancrelipase

Follow your doctor's advice regarding any dietary restrictions, fluid intake, or activity limitations. Regular checkups and monitoring are important to ensure the medication is working effectively and to detect any potential problems early.

Possible Side Effects

Seek immediate medical attention if you experience any signs of an allergic reaction, such as:

• Hives
• Difficulty breathing
• Swelling of the face, lips, tongue, or throat

Contact your doctor promptly if you experience severe or unusual stomach pain. This could indicate a rare but serious bowel disorder.

Common, less serious side effects can include:

• Nausea or vomiting
• Mild stomach pain or upset
• Diarrhea or constipation
• Bloating or gas
• Greasy stools
• Rectal irritation
• Headache or dizziness
• Cough
• Weight loss

Storage Instructions

Store Pancrelipase in its original container at room temperature, away from moisture and heat. The medication can also be stored between 77 and 104 degrees Fahrenheit (25-40 degrees Celsius) for up to 30 days. After 30 days, discard any unused medication stored at these higher temperatures.

Do not use Pancrelipase if it has been exposed to temperatures above 104°F (40°C).