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    Esbriet

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    Esbriet 200 mg

    Package Per Pill Special Price
    120 pills
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    		 $2.73
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    90 pills
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    Esbriet (Pirfenidone): Comprehensive Information for IPF Treatment

    Esbriet, containing pirfenidone, is a medication specifically designed for the treatment of adults diagnosed with Idiopathic Pulmonary Fibrosis (IPF). IPF is a chronic and progressive lung disease characterized by inflammation and the development of scar tissue (fibrosis) in the lungs. This scarring makes it difficult for the lungs to function properly, leading to shortness of breath and reduced oxygen levels in the blood. Esbriet works by slowing down the progression of scar tissue build-up in the lungs. While it is not a cure for IPF, it can significantly slow down the rate at which the condition worsens, helping patients maintain a better quality of life for longer.

    What is Idiopathic Pulmonary Fibrosis (IPF)?

    Idiopathic Pulmonary Fibrosis (IPF) is a specific type of chronic, progressive fibrosing interstitial lung disease of unknown cause. It primarily affects adults over the age of 50. The term "idiopathic" means the cause is unknown. The prognosis for IPF varies, but it's generally a serious condition that requires careful management.

    Esbriet: How it Works for IPF

    Pirfenidone, the active ingredient in Esbriet, is believed to work by reducing the production of certain growth factors and pro-inflammatory mediators involved in the development of fibrosis. This helps to slow down the formation of scar tissue in the lungs, thereby preserving lung function.

    Dosage and Administration

    Always take Esbriet exactly as prescribed by your doctor. The dosage may be adjusted based on individual needs and tolerance. It is typically taken three times a day with food to minimize side effects such as nausea and dizziness. Consistency in timing is important for optimal results. This medicine is intended for long-term use, and it's crucial to continue taking it as directed, even if you feel well.

    Detailed Dosage Instructions:

    • Initial Dose: Your doctor will likely start you on a lower dose and gradually increase it over several weeks to the target dose.
    • Maintenance Dose: The typical maintenance dose is 801 mg three times daily (2403 mg total daily dose).
    • Administration: Swallow the tablets or capsules whole with water. Do not crush, chew, or break them.
    • With Food: Always take Esbriet with food to help reduce nausea and other gastrointestinal side effects.
    • Missed Dose: If you miss a dose, take it as soon as you remember, unless it is close to the time for your next dose. Do not double the dose to catch up.

    Important Precautions Before Taking Esbriet

    Before starting Esbriet, it's essential to inform your doctor about all your medical conditions, including:

    • Liver Problems: Esbriet can affect liver function. Regular liver function tests are necessary.
    • Kidney Problems: Kidney disease may affect how your body processes Esbriet.
    • Smoking: Smoking can reduce the effectiveness of Esbriet. Quitting smoking is strongly recommended.
    • Pregnancy and Breastfeeding: The safety of Esbriet during pregnancy and breastfeeding is not established. Discuss the risks and benefits with your doctor. Use effective contraception during treatment.
    • Other Medications: Inform your doctor about all other medications you are taking, including prescription drugs, over-the-counter medicines, and herbal supplements.

    Contraindications: When Not to Use Esbriet

    Esbriet is contraindicated in patients with:

    • Known hypersensitivity to pirfenidone or any of the excipients.
    • Severe hepatic impairment.
    • Severe renal impairment or end-stage renal disease requiring dialysis.
    • Concomitant use of fluvoxamine (a strong CYP1A2 inhibitor), unless fluvoxamine is discontinued before initiating Esbriet treatment, or the Esbriet dosage is reduced.

    Potential Side Effects of Esbriet

    Like all medications, Esbriet can cause side effects. The most common side effects include:

    • Gastrointestinal Issues: Nausea, vomiting, diarrhea, indigestion, heartburn, abdominal pain, loss of appetite, weight loss.
    • Skin Reactions: Photosensitivity (increased sensitivity to sunlight), rash.
    • General Symptoms: Fatigue, headache, dizziness, difficulty sleeping, upper respiratory tract infections, sinus infections.

    Serious Side Effects: Esbriet can cause serious side effects. Contact your doctor immediately if you experience any of the following:

    • Liver Problems: Symptoms may include yellowing of the skin or eyes (jaundice), dark urine, abdominal pain, and fatigue.
    • Severe Skin Reactions: Blisters, rash, sores in the mouth, hives, or any other severe skin symptoms.
    • Stomach Problems: Persistent or worsening nausea, vomiting, diarrhea, indigestion, heartburn, or stomach pain.

    Managing Photosensitivity

    Esbriet can make your skin more sensitive to sunlight, sunlamps, and tanning beds. To minimize the risk of sunburn:

    • Avoid prolonged exposure to sunlight.
    • Use a broad-spectrum sunscreen with an SPF of 50 or higher.
    • Wear protective clothing, such as a hat and long sleeves, when outdoors.

    Drug Interactions

    Esbriet can interact with other medications. Be sure to tell your doctor about all medications you are taking, including:

    • CYP1A2 Inhibitors: Medications that inhibit the CYP1A2 enzyme, such as fluvoxamine and ciprofloxacin, can increase the levels of Esbriet in your blood, potentially increasing the risk of side effects. Dose adjustments may be necessary.
    • Other Photosensitizing Medications: Avoid taking Esbriet with other medicines that can make your skin sensitive to the sun.

    Overdose Information

    Do not take more than the prescribed dose of Esbriet. If you suspect an overdose, seek immediate medical attention.

    Storage Instructions

    • Store Esbriet capsules and tablets at room temperature, 77°F (25°C).
    • Keep in a tightly closed container.
    • Throw away any Esbriet that is out of date or no longer needed.
    • Keep Esbriet and all medicines out of reach of children.

    Esbriet: Where to Buy and How to Order

    Esbriet (pirfenidone) is available for purchase through our online pharmacy. We offer competitive pricing and convenient delivery options. Browse our selection and order Esbriet online today. Consult with your doctor to determine if Esbriet is right for you. We offer a variety of IPF medications and pulmonary fibrosis treatment options.

    Cost of Esbriet

    The price of Esbriet can vary depending on the dosage and quantity. Check our website for current pricing and potential discounts.

    Is Esbriet Covered by Insurance?

    Coverage for Esbriet varies depending on your insurance plan. Contact your insurance provider to determine if Esbriet is covered under your specific plan.

    FAQ About Esbriet (Pirfenidone)

    1. What is Esbriet used for?

      Esbriet (pirfenidone) is used to treat adults with idiopathic pulmonary fibrosis (IPF).

    2. How should I take Esbriet?

      Take Esbriet exactly as your doctor prescribes, usually three times a day with food.

    3. What are the common side effects of Esbriet?

      Common side effects include nausea, fatigue, and photosensitivity.

    4. What should I do if I miss a dose?

      Take the missed dose as soon as you remember, unless it's almost time for your next dose. Do not double the dose.

    5. Can Esbriet cure IPF?

      No, Esbriet is not a cure for IPF, but it can slow down the progression of the disease.

    6. Where can I buy Esbriet online?

      Esbriet is available for purchase through our online pharmacy.

    Disclaimer: This information is not a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider if you have questions about your health or treatment.

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