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Glucovance

Glucovance 5mg/500mg

Package Per Pill Special Price
360 pills
Free Express Delivery
$0.95
$612 -45%
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270 pills
Free Express Delivery
$1.20
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180 pills
Free Regular Delivery
$1.27
$306 -26%
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120 pills
$1.33
$204 -22%
Only $160
90 pills
$1.40
$153 -18%
Only $126
60 pills
$1.50
$102 -12%
Only $90
30 pills
$1.70
Only $51

Glucovance 2.5mg/400mg

Package Per Pill Special Price
360 pills
Free Regular Delivery
$0.80
$576 -50%
Only $288
270 pills
Free Regular Delivery
$1.00
$432 -38%
Only $270
180 pills
$1.08
$288 -33%
Only $194
120 pills
$1.16
$192 -28%
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90 pills
$1.23
$144 -23%
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60 pills
$1.35
$96 -16%
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30 pills
$1.60
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Glucovance: Comprehensive Information for Effective Diabetes Management

Glucovance is a prescription medication combining two powerful oral hypoglycemic agents, metformin and glibenclamide, to effectively manage type 2 diabetes. This combination therapy is designed to help control blood sugar levels when diet and exercise alone are not sufficient. Understanding how Glucovance works, its proper usage, and potential side effects is crucial for safe and effective treatment.

Understanding Glucovance: How it Works

Glucovance leverages the synergistic effects of metformin and glibenclamide:

  • Metformin: Belongs to the biguanide class and works by:
    • Increasing insulin sensitivity in peripheral tissues, allowing cells to utilize glucose more effectively.
    • Decreasing glucose absorption in the gastrointestinal tract, reducing the amount of glucose entering the bloodstream.
    • Inhibiting glucose production in the liver, further lowering blood sugar levels.
  • Glibenclamide: A sulfonylurea derivative that:
    • Stimulates insulin secretion from the beta cells of the pancreas, helping to lower blood glucose.

Uses of Glucovance

Glucovance is primarily used to treat type 2 diabetes (non-insulin-dependent diabetes) in conjunction with a healthy diet and regular exercise. It helps to lower blood sugar levels and improve glycemic control in adults.

Glucovance Dosage and Administration

Follow these guidelines for proper Glucovance usage:

  • Take Glucovance orally, usually twice daily, with meals and a full glass of water.
  • Adhere to your doctor's prescribed dosage and schedule to achieve optimal blood sugar control.
  • Take Glucovance at the same times each day to maintain consistent drug levels in your body.

Important Precautions While Taking Glucovance

Consider these precautions to ensure safe Glucovance use:

  • Alcohol: Avoid alcoholic beverages while taking Glucovance, as alcohol can increase the risk of hypoglycemia (low blood sugar).
  • Medical Conditions: Inform your doctor if you have any fever, thyroid gland disorders, pituitary or adrenal gland dysfunction, or severe breathing problems before starting Glucovance.
  • Pregnancy and Breastfeeding: Discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding before using Glucovance.
  • Blood Disorders: Disclose any existing blood problems, such as anemia or vitamin B-12 deficiency, to your physician.

When Glucovance is Not Recommended: Contraindications

Glucovance is contraindicated (not recommended) in the following conditions:

  • Hypersensitivity to metformin, glibenclamide, or other sulfonylurea derivatives.
  • Type 1 diabetes.
  • Diabetic ketoacidosis, diabetic precoma, or diabetic coma.
  • Kidney failure or kidney dysfunction.
  • Severe conditions that may lead to kidney dysfunction (e.g., dehydration, severe infection, shock).
  • Acute or chronic diseases accompanied by tissue hypoxia (lack of oxygen).
  • Cardiac or respiratory failure.
  • Recent myocardial infarction (heart attack).
  • Hepatic impairment (liver problems).
  • Porphyria.
  • Pregnancy and breastfeeding.
  • Co-administration with miconazole (anti-fungal medication).
  • Infectious diseases.
  • Extensive surgery, trauma, or burns.
  • Conditions requiring insulin therapy.
  • Abnormal liver function.
  • Chronic alcoholism or acute alcohol intoxication.
  • Lactic acidosis (a serious metabolic condition).
  • Usage 48 hours before and after radioisotope or radiological examinations with iodinated contrast agents.
  • Patients over 60 years old or those performing hard physical work (increased risk of lactic acidosis).
  • Low glucose diet.

Possible Side Effects of Glucovance

Be aware of potential side effects while taking Glucovance:

  • Common Side Effects: Nausea, vomiting, gas, bloating, diarrhea, loss of appetite, swelling, rapid weight gain.
  • Serious Side Effects (Seek Immediate Medical Attention):
    • Lactic acidosis: shortness of breath, stomach pain, weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, light-headedness, fainting.
    • Allergic reaction: hives, swelling, rash.

Glucovance Drug Interactions

Glucovance can interact with other medications. Inform your doctor about all medications you are taking, including:

  • Cimetidine (Tagamet): Can increase blood levels of Glucovance.
  • Alcohol: Incompatible with Glucovance.
  • Indirect anticoagulants and Cimetidine: Use with caution.
  • Furosemide: Glucovance enhances the metabolism of Furosemide.
  • Sulfonylurea derivatives, insulin, acarbose, MAO inhibitors, ACE inhibitors (e.g., captopril), oxytetracycline, cyclophosphamide, and salicylates: These medications may increase the effects of Glucovance.
  • Thyroid medicines, birth control pills, other hormones, epinephrine, glucagon, thiazide diuretics, nicotinic acid derivatives: These medications may decrease the hypoglycemic effect of Glucovance.
  • Azole antifungals (e.g., fluconazole): Can interact with Glucovance.

Managing a Missed Dose of Glucovance

If you miss a dose of Glucovance:

  • Take it as soon as you remember.
  • Do not take a double dose to make up for the missed one.
  • Take your next dose at the regularly scheduled time.

Recognizing and Responding to a Glucovance Overdose

Symptoms of a Glucovance overdose are related to low blood sugar (hypoglycemia):

  • Hunger, tremors, confusion, irritability, drowsiness, headache, weakness, sweating, fast heartbeat, seizure.
  • Always have a source of sugar readily available.
  • If you experience any of these symptoms or any unusual symptoms, call your doctor immediately.

Proper Storage of Glucovance

Store Glucovance properly to maintain its effectiveness:

  • Store at room temperature between 20-25°C (68-77°F).
  • Protect from moisture, heat, and sunlight.
  • Do not store in the bathroom.
  • Keep out of reach of children and pets.

Glucovance: Buy Online and Save

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Alternative Diabetes Medications

While Glucovance is an effective treatment option, other diabetes medications are also available. Consult with your doctor to determine the best treatment plan for your individual needs. Explore our selection of diabetes medications online, including [link to other diabetes medication category] .

FAQ About Glucovance

  • What is Glucovance used for? Glucovance is used to treat type 2 diabetes by lowering blood sugar levels.
  • How should I take Glucovance? Take Glucovance twice daily with meals and a full glass of water, as directed by your doctor.
  • What are the side effects of Glucovance? Common side effects include nausea, vomiting, gas, and diarrhea. Serious side effects include lactic acidosis and allergic reactions. Seek immediate medical attention if you experience any serious side effects.
  • Can I drink alcohol while taking Glucovance? No, it is best to avoid alcohol while taking Glucovance, as it can increase the risk of hypoglycemia.
  • Where can I buy Glucovance? You can purchase Glucovance online from our pharmacy with a valid prescription.

This information is for informational purposes only and should not be considered medical advice. Always consult with your healthcare provider for any questions or concerns about your health or treatment.

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