Afipran (other name Metoclopramide)

Gastrointestinal Tract

Afipran (other name Metoclopramide) 10mg

Package	Per Pill	Special Price
360 pills Free Regular Delivery	$0.56	~~$306~~ -34% Only $202
270 pills	$0.58	~~$230~~ -32% Only $157
180 pills	$0.62	~~$153~~ -28% Only $111
120 pills	$0.68	~~$102~~ -21% Only $81
90 pills	$0.73	~~$77~~ -14% Only $66
60 pills	$0.85	Only $51

Product Description

Metoclopramide is a medication used to treat a variety of gastrointestinal issues. It functions as both a gastrointestinal stimulant and an antiemetic, helping to regulate digestive processes and alleviate nausea. Available by prescription, Metoclopramide is offered in various forms, including tablets and solutions.

Common Use & Health Benefits

Metoclopramide is primarily prescribed for:

Gastroesophageal Reflux Disease (GERD): Provides relief for patients who haven't responded adequately to other GERD treatments, reducing the backward flow of stomach acid into the esophagus.
Diabetic Gastroparesis: Eases symptoms associated with slowed stomach emptying in diabetic patients, promoting proper digestion and reducing discomfort.
Nausea and Vomiting: Prevents and manages nausea and vomiting related to chemotherapy, surgery, or other medical conditions.
Small Bowel Intubation: Facilitates the passage of tubes into the small intestine for diagnostic or therapeutic purposes.

The health benefits of Metoclopramide extend to improved digestion, reduced nausea, and enhanced overall comfort for patients dealing with gastrointestinal disorders.

Dosage and Directions for Use

The correct dosage and administration of Metoclopramide are crucial for its effectiveness and safety. Always follow your doctor's instructions precisely. General guidelines include:

Timing: Take Metoclopramide approximately 30 minutes before meals to maximize its impact on digestion.
Administration: Administer Metoclopramide orally with a full glass of water.
Consistency: Adhere to the prescribed dosage schedule, and do not stop taking the medication without consulting your healthcare provider.
Missed Dose: If you miss a dose, take it as soon as you remember. If it is near the time for your next scheduled dose, skip the missed dose and continue with your regular dosing regimen. Do not double up on doses.
Duration of Use: Metoclopramide is typically used for short-term treatment. Long-term use should be discussed with your doctor.

Storage Information

Proper storage ensures the medication's stability and effectiveness:

Temperature: Store Metoclopramide at room temperature, ideally between 68°F and 77°F (20°C and 25°C).
Environment: Keep the medication in a tightly closed container, away from direct heat, moisture, and light. Avoid storing it in the bathroom.
Safety: Keep Metoclopramide out of reach of children and pets.

Safety Information and Important Considerations

Before taking Metoclopramide, it's essential to be aware of potential risks and interactions:

Contraindications: Do NOT use Metoclopramide if you have a known allergy to it or any of its ingredients, if you have a history of seizures, gastrointestinal bleeding, blockage, perforation, or pheochromocytoma (adrenal gland tumor).
Drug Interactions: Inform your doctor about all medications you are currently taking, including prescription, over-the-counter, and herbal supplements. Specific drugs to be cautious about include MAO inhibitors, anticholinergics, narcotic pain medications, and others mentioned in the original description.
Medical Conditions: Disclose any existing medical conditions, especially mental health issues (e.g., depression), asthma, heart failure, high blood pressure, diabetes, Parkinson's disease, kidney or liver problems, breast cancer, or low levels of methemoglobin reductase.
Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Metoclopramide may pass into breast milk and could affect the nursing infant.
Alcohol and Sedatives: Avoid alcohol and other sedatives while taking Metoclopramide, as they can intensify drowsiness and dizziness.
Long-Term Use: Do not take Metoclopramide for more than 12 weeks without consulting your doctor, due to the risk of tardive dyskinesia.
Diabetes: Metoclopramide can affect blood sugar levels in diabetic patients. Monitor your blood sugar closely and adjust your diabetes medication as needed.
Neuroleptic Malignant Syndrome (NMS): Be vigilant for symptoms of NMS, such as fever, muscle stiffness, confusion, and irregular heartbeat. Seek immediate medical attention if these occur.
Tardive Dyskinesia: Long-term use can lead to tardive dyskinesia, characterized by uncontrollable muscle movements. Report any such movements to your doctor immediately.
Mental Health: Watch for any new or worsening mental health symptoms, such as depression or suicidal thoughts.
Prolactin Levels: Metoclopramide can increase prolactin levels, potentially leading to symptoms like enlarged breasts, missed periods, or nipple discharge.
Elderly Patients: Exercise caution when using Metoclopramide in elderly patients, as they may be more susceptible to side effects like drowsiness, confusion, and uncontrolled muscle movements.
Children: Metoclopramide is not generally recommended for children due to safety concerns.

Possible Side Effects

As with any medication, Metoclopramide can cause side effects. Common side effects include:

Decreased energy
Diarrhea
Dizziness
Drowsiness
Headache
Nausea
Restlessness
Tiredness
Trouble sleeping

Seek immediate medical attention if you experience any of the following severe side effects:

Severe allergic reactions (rash, hives, itching, difficulty breathing, swelling)
Abnormal thinking
Confusion
Dark urine
Decreased balance or coordination
Decreased sexual ability
Fast, slow, or irregular heartbeat
Fever
Hallucinations
Loss of bladder control
Mental or mood changes (e.g., depression, anxiety, agitation)
Seizures
Severe or persistent dizziness, headache, or trouble sleeping
Severe or persistent restlessness
Shortness of breath
Stiff or rigid muscles
Sudden increased sweating
Sudden, unusual weight gain
Suicidal thoughts or actions
Swelling of the arms, legs, or feet
Uncontrolled muscle spasms or movements
Vision changes
Yellowing of the skin or eyes (jaundice)

This is not an exhaustive list of all possible side effects. If you notice any unusual symptoms, contact your healthcare provider promptly.

Frequently Asked Questions (FAQ) about Metoclopramide

What is Metoclopramide used for?: Metoclopramide is used to treat GERD, diabetic gastroparesis, nausea, and vomiting, and to facilitate small bowel intubation.
How should I take Metoclopramide?: Take Metoclopramide 30 minutes before meals, as directed by your doctor. Follow the prescribed dosage schedule.
What should I do if I miss a dose?: Take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule.
Can I drink alcohol while taking Metoclopramide?: No, avoid alcohol as it can increase drowsiness and dizziness.
What are the common side effects of Metoclopramide?: Common side effects include drowsiness, dizziness, nausea, and headache.
When should I seek medical attention?: Seek immediate medical attention for severe allergic reactions, muscle spasms, mental health changes, or symptoms of neuroleptic malignant syndrome.
Can pregnant or breastfeeding women take Metoclopramide?: Consult your doctor before using Metoclopramide if you are pregnant or breastfeeding.
How long can I take Metoclopramide?: Do not take Metoclopramide for more than 12 weeks without consulting your doctor.

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