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Digoxina (other name Digoxin)
Digoxina (other name Digoxin) 0.25mg
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360 pills
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$0.42 |
Only $152
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270 pills
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$0.43 |
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180 pills
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$0.46 |
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120 pills
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$0.49 |
Only $59
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90 pills
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$0.53 |
Only $48
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Digoxin: Comprehensive Information for Patients
Product Description
Digoxin is a medication primarily used in the treatment of heart failure and for controlling the heart rate in individuals suffering from chronic atrial fibrillation, a condition characterized by an irregular and often rapid heart rhythm. It belongs to a class of drugs known as digitalis glycosides.
Mechanism of Action
Digoxin exerts its therapeutic effects through two primary mechanisms:
- Increased Force of Heart Contraction (Positive Inotropy): Digoxin enhances the contractility of the heart muscle, allowing it to pump blood more efficiently with each beat.
- Slowed Heart Rate (Negative Chronotropy): Digoxin slows down the electrical conduction within the heart, particularly at the atrioventricular (AV) node. This helps to control and reduce the heart rate, especially in cases of atrial fibrillation where the heart beats too quickly and erratically.
Common Uses
Digoxin is prescribed for the following conditions:
- Heart Failure: To improve the heart's ability to pump blood effectively, reducing symptoms such as shortness of breath, swelling in the ankles and legs, and fatigue.
- Atrial Fibrillation: To slow the heart rate and control irregular heart rhythms, helping to alleviate symptoms like palpitations, chest pain, and lightheadedness.
Dosage and Administration
Important: Digoxin dosage is highly individualized and must be determined by your healthcare provider. Never adjust your dosage without consulting your doctor.
General guidelines for taking Digoxin:
- Follow Doctor's Instructions: Always take Digoxin exactly as prescribed by your doctor. Adhere strictly to the prescribed dosage and schedule.
- Do Not Exceed Recommended Dose: Do not take more Digoxin than prescribed, and do not take it for longer than recommended.
- Consistency: Take Digoxin at the same time each day to maintain consistent blood levels.
- With Water: Swallow the tablet with a full glass of water.
- Regular Monitoring: Digoxin levels in your blood, as well as your kidney function, may need to be monitored regularly to ensure the medication is working effectively and to prevent toxicity. Keep all scheduled appointments.
- Continue Taking as Directed: Even if you feel better, continue taking Digoxin as directed. Do not stop taking it without consulting your doctor, as abrupt discontinuation can worsen your condition.
- Missed Dose: If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
Storage Information
Proper storage of Digoxin is crucial to maintain its effectiveness and safety:
- Temperature: Store Digoxin at room temperature, ideally around 77°F (25°C). Brief storage at temperatures between 59°F and 86°F (15°C and 30°C) is acceptable.
- Protection from Elements: Keep Digoxin away from heat, moisture, and direct light.
- Avoid Bathroom Storage: Do not store Digoxin in the bathroom, as humidity can degrade the medication.
- Child and Pet Safety: Keep Digoxin out of the reach of children and pets. It is a potent medication and can be dangerous if ingested accidentally.
Safety Information: Contraindications and Precautions
It is essential to be aware of the safety information associated with Digoxin to minimize potential risks:
Do NOT use Digoxin if:
- You are allergic to Digoxin or any other digitalis-based medications.
- You have beriberi heart disease (heart disease caused by thiamine deficiency).
- You have certain types of heart rhythm problems, such as ventricular fibrillation.
Consult your doctor before using Digoxin if you have any of the following conditions:
- Pregnancy or Breastfeeding: If you are pregnant, planning to become pregnant, or are breastfeeding, discuss the potential risks and benefits of Digoxin with your doctor.
- Medical Conditions: Inform your doctor about any pre-existing medical conditions, including:
- Severe heart failure
- Inflammation of the heart (myocarditis)
- Coronary artery disease
- Recent heart attack
- Heart block
- Premature ventricular contractions (PVCs)
- Certain abnormal heart rhythms
- Fainting spells due to heart problems
- Kidney, liver, or lung problems
- Thyroid problems
- Electrolyte imbalances (low levels of calcium, magnesium, or potassium; high levels of potassium or calcium)
- Medications and Supplements: Disclose all medications, herbal preparations, and dietary supplements you are currently taking to your doctor or pharmacist.
- Allergies: Inform your doctor about any allergies you have, particularly to medications, foods, or other substances.
Drug Interactions
Many medications can interact with Digoxin, potentially affecting its effectiveness or increasing the risk of side effects. It is crucial to inform your healthcare provider of all medications you are taking. Some notable interactions include:
- Increased Digoxin Effects: Amiodarone, amphotericin B, anticholinergics (e.g., propantheline), beta-blockers (e.g., propranolol), bupivacaine, calcium, certain stimulants (e.g., albuterol, amphetamine, pseudoephedrine), cyclosporine, diltiazem, diphenoxylate, diuretics (e.g., hydrochlorothiazide, furosemide), indomethacin, itraconazole, macrolides (e.g., erythromycin), propafenone, quinidine, quinine, spironolactone, succinylcholine, tetracyclines (e.g., doxycycline), thioamines (e.g., methimazole), and verapamil. These medications can increase Digoxin levels in the blood, potentially leading to toxicity.
- Decreased Digoxin Effects: Acarbose, certain anticancer medications, cholestyramine, colestipol, kaolin-pectin, metoclopramide, penicillamine, rifampin, sulfasalazine, and thyroid hormones (e.g., levothyroxine). These medications can decrease Digoxin absorption or increase its elimination, reducing its effectiveness.
- Variable Digoxin Effects: Oral aminoglycosides (e.g., neomycin) can either increase or decrease Digoxin's effects.
- Lab Test Interference: Spironolactone can interfere with certain lab tests used to measure Digoxin blood levels, leading to inaccurate results.
This is not an exhaustive list of all potential drug interactions. Always consult your healthcare provider to ensure the safety of your medication regimen.
Important Safety Considerations
- Dizziness and Blurred Vision: Digoxin may cause dizziness or blurred vision. Exercise caution when driving or operating machinery until you know how the medication affects you. Avoid alcohol consumption, as it can worsen these effects.
- Medical and Dental Procedures: Inform your doctor or dentist that you are taking Digoxin before any medical or dental procedures, emergency care, or surgery.
- Lab Monitoring: Regular lab tests, including electrocardiograms (ECGs), electrolyte levels, and Digoxin blood levels, are essential to monitor your condition and detect potential side effects. Attend all scheduled appointments.
- Elderly Patients: Elderly individuals may be more sensitive to the effects of Digoxin and require closer monitoring.
- Premature Infants: Use Digoxin with extreme caution in premature or immature infants, as they are also more susceptible to its effects.
- Overdose: Accidental ingestion of Digoxin by children or receiving an excessive dose can be life-threatening. Seek immediate medical attention in case of an overdose.
- Pregnancy and Breastfeeding: Discuss the risks and benefits of Digoxin use with your doctor if you are pregnant or breastfeeding. Digoxin can pass into breast milk and may affect the nursing infant.
Possible Side Effects
Like all medications, Digoxin can cause side effects. Many people experience no side effects, or only minor ones. However, it's important to be aware of potential adverse reactions.
Common Side Effects (usually mild and temporary):
- Diarrhea
- Nausea
Serious Side Effects (seek immediate medical attention if you experience any of these):
- Allergic Reactions: Rash, hives, itching, difficulty breathing, chest tightness, swelling of the mouth, face, lips, or tongue.
- Vision Changes: Blurred vision, yellow vision, or other visual disturbances.
- Mental and Neurological Changes: Confusion, hallucinations, mood changes (e.g., depression).
- Heart Rhythm Problems: Fast, slow, or irregular heartbeat.
- Gastrointestinal Issues: Severe or persistent nausea, vomiting, or stomach pain.
- Bleeding: Unusual bruising or bleeding.
- General Weakness: Unusual tiredness or weakness.
This is not a complete list of all possible side effects. If you experience any unusual symptoms while taking Digoxin, contact your healthcare provider immediately.
FAQ About Digoxin
What should I do if I think I'm experiencing Digoxin toxicity?
If you suspect Digoxin toxicity (e.g., severe nausea, vomiting, vision changes, irregular heartbeat), seek immediate medical attention. Go to the nearest emergency room or call your doctor right away.
Can I drink alcohol while taking Digoxin?
It's generally advisable to limit or avoid alcohol consumption while taking Digoxin, as alcohol can worsen side effects like dizziness and blurred vision.
How long does it take for Digoxin to start working?
The onset of action varies depending on the individual and the condition being treated. You may start to feel better within a few days, but it can take several weeks to achieve the full therapeutic effect. Follow your doctor's instructions and attend all follow-up appointments.
What happens if I stop taking Digoxin suddenly?
Stopping Digoxin suddenly can worsen your heart condition and lead to serious complications. Always consult your doctor before discontinuing Digoxin treatment.
Can Digoxin cure heart failure or atrial fibrillation?
Digoxin does not cure heart failure or atrial fibrillation, but it can help manage the symptoms and improve your quality of life. It's essential to follow your doctor's recommendations and continue taking Digoxin as prescribed.
Are there any lifestyle changes I should make while taking Digoxin?
Maintaining a healthy lifestyle is crucial for managing heart conditions. This includes following a balanced diet, engaging in regular exercise (as tolerated), managing stress, and avoiding smoking. Consult your doctor for personalized recommendations.
What are the signs and symptoms of Digoxin toxicity?
Signs of Digoxin toxicity include nausea, vomiting, diarrhea, loss of appetite, vision changes (blurred or yellow vision), confusion, dizziness, irregular heartbeat, and palpitations. If you experience any of these symptoms, seek immediate medical attention.
How is Digoxin different from other heart medications?
Digoxin is a unique medication with specific effects on heart contractility and heart rate. Other heart medications, such as ACE inhibitors, beta-blockers, and diuretics, work through different mechanisms. Your doctor will determine the most appropriate medications for your individual condition.
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