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Glibenclamide (other name Micronase)

Glibenclamide (other name Micronase) 5mg

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Glyburide: Uses, Side Effects, and Important Safety Information

Glyburide is an oral diabetes medicine that helps control blood sugar levels. It is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes. This medication belongs to a class of drugs known as sulfonylureas, which work by stimulating the pancreas to release more insulin.

What is Glyburide Used For?

  • Type 2 Diabetes Management: Glyburide is a cornerstone in managing type 2 diabetes, helping to regulate blood glucose levels when diet and exercise alone are not enough.
  • Improved Blood Sugar Control: It aids in maintaining stable blood sugar levels, reducing the risk of long-term complications associated with diabetes.

Important Information Before Taking Glyburide

Before starting glyburide, inform your doctor about all your medical conditions, especially:

  • Kidney or liver disease
  • Adrenal or pituitary gland disorders
  • G6PD deficiency
  • If you are pregnant or breastfeeding

Glyburide can cause hypoglycemia (low blood sugar). Be aware of the symptoms and how to treat them. Tell your doctor about all other medications you use, especially:

  • Other diabetes medications
  • Sulfa drugs
  • Aspirin or other salicylates
  • Blood thinners
  • MAO inhibitors
  • Beta-blockers

Dosage and Administration

Take glyburide exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

  • Glyburide is usually taken once or twice daily with meals.
  • Follow your doctor's instructions carefully.
  • Your blood sugar will need to be checked often, and you may also need to test the glucose in your urine.
  • Low blood sugar (hypoglycemia) can happen to anyone taking glyburide.

Glyburide Side Effects

SIDE EFFECTS

Stop using glyburide and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking this medication and call your doctor at once if you have any of these serious side effects:

  • Nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • Pale skin, confusion or weakness;
  • Easy bruising or bleeding, purple or red pinpoint spots under your skin; or
  • Headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Less serious side effects may include:

  • Mild nausea, heartburn, feeling full;
  • Joint or muscle pain;
  • Blurred vision; or
  • Mild itching or skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Drug Interactions

Glyburide can interact with many other medications, potentially altering their effects or increasing the risk of side effects. Be sure to tell your doctor about all the medications you are taking, including:

  • Insulin or other oral diabetes medications
  • Certain antibiotics, such as sulfonamides
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Aspirin
  • Blood thinners like warfarin
  • Certain medications for high blood pressure
  • Cholesterol-lowering drugs

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of glyburide can cause severe hypoglycemia.

What to avoid

  • Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.
  • Avoid exposure to sunlight or tanning beds. Glyburide can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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Frequently Asked Questions (FAQ) about Glyburide

What should I do if I experience low blood sugar while taking glyburide?
If you experience symptoms of low blood sugar (such as sweating, shaking, rapid heartbeat, hunger, blurred vision, or tingling in your hands/feet), quickly consume a source of sugar like glucose tablets, fruit juice, or a non-diet soda. Check your blood sugar and eat a snack or meal to prevent your blood sugar from dropping again.
Can I drink alcohol while taking glyburide?
It is generally recommended to avoid or limit alcohol consumption while taking glyburide. Alcohol can lower blood sugar levels and may interfere with the medication's effectiveness or increase the risk of side effects.
What should I do if I miss a dose of glyburide?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
How should I store glyburide?
Store glyburide at room temperature, away from heat, light, and moisture. Keep out of reach of children and pets.
Is glyburide safe for pregnant women?
Discuss the use of glyburide with your doctor if you are pregnant or planning to become pregnant. Your doctor will advise you on the best course of treatment for your diabetes during pregnancy.

Disclaimer: This information is intended for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.

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