Isonid (other name Isoniazid)

AntiDepressants

Isonid (other name Isoniazid) 300mg

Package	Per Pill	Special Price
360 pills	$0.38	~~$180~~ -25% Only $136
270 pills	$0.39	~~$135~~ -22% Only $106
180 pills	$0.42	~~$90~~ -17% Only $75
120 pills	$0.46	~~$60~~ -9% Only $55
90 pills	$0.50	Only $45

Isoniazid: Your Comprehensive Guide for Treatment and Prevention of Tuberculosis

Are you looking for an effective medication to treat or prevent tuberculosis (TB)? Isoniazid is a powerful antibacterial agent primarily used in the treatment and prevention of TB. This comprehensive guide provides detailed information about Isoniazid, including its uses, dosage, safety information, and potential side effects.

What is Isoniazid?

Isoniazid is an antibacterial medication that specifically targets and kills TB organisms. It is a first-line treatment for both active TB disease and latent TB infection. In addition to its antibacterial properties, Isoniazid was also one of the first antidepressants discovered. It can also be used in the treatment of a BCG-oma.

Common Uses of Isoniazid

Treatment of Tuberculosis (TB): Isoniazid is a cornerstone medication in TB treatment regimens. It is typically used in combination with other anti-TB drugs to ensure effective eradication of the bacteria.
Prevention of Tuberculosis (TB): For individuals at high risk of developing TB (e.g., those with latent TB infection, close contacts of active TB cases), Isoniazid can be prescribed as a preventive measure.
Treatment of BCG-oma: Isoniazid can also be used to treat a BCG-oma, a rare complication that can occur after BCG vaccination.

Isoniazid Dosage and Administration

The correct dosage and administration of Isoniazid are crucial for its effectiveness and to minimize potential side effects. Always follow your doctor's instructions carefully.

Dosage Guidelines:

Take Isoniazid exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting your healthcare provider.
Administer each dose with a full glass (8 ounces) of water.
Take Isoniazid on an empty stomach, either 1 hour before or 2 hours after meals. If you experience nausea, discuss with your doctor whether taking it with food is appropriate.
Complete the full course of Isoniazid treatment, even if you start feeling better. Discontinuing prematurely can lead to incomplete eradication of the infection and antibiotic resistance.
Take Isoniazid regularly to achieve the maximum benefit.
Your doctor may recommend a daily vitamin B6 (pyridoxine) supplement to prevent nerve-related side effects (numbness and tingling).
Regular blood tests and medical evaluations may be required to monitor your progress and detect any potential side effects.

Missed Dose:

If you miss a dose of Isoniazid, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to compensate for a missed one.

Isoniazid: Important Safety Information

Your safety is paramount when taking Isoniazid. Be aware of the following precautions and potential interactions.

Contraindications:

Do NOT use Isoniazid if:

You are allergic to any of its ingredients or have experienced severe side effects (e.g., drug fever, chills, arthritis) from previous use.
You have severe liver damage, active liver disease, or liver damage caused by previous Isoniazid use.
You have a history of hepatitis caused by any medication.

If any of the above conditions apply to you, consult your doctor or healthcare provider immediately.

Precautions:

Inform your doctor or pharmacist about any existing medical conditions, especially if any of the following apply:

Pregnancy, planning to become pregnant, or breastfeeding.
Any prescription or nonprescription medications, herbal preparations, or dietary supplements you are currently taking.
Allergies to medicines, foods, or other substances.
Diabetes, kidney problems, nerve problems (neuropathy) or risk factors for neuropathy, HIV, or a history of liver problems.
A history of alcohol or other substance abuse, unsanitary injectable drug habits, or daily alcohol consumption.
Age over 35 years, recent childbirth, or previous use of Isoniazid.

Drug Interactions:

Certain medications can interact with Isoniazid. Disclose all medications you are taking to your healthcare provider, particularly:

Acetaminophen, anticoagulants (e.g., warfarin), carbamazepine, hydantoins (e.g., phenytoin), rifampin, theophylline, or valproic acid. Isoniazid may increase the risk of side effects from these drugs.
Ketoconazole: Isoniazid may decrease its effectiveness.

This list may not be exhaustive. Consult your healthcare provider to ensure that Isoniazid does not interact with any other medications you are taking. Always check with your doctor before starting, stopping, or changing the dosage of any medication.

Important Safety Considerations:

Alcohol: Consult your doctor before consuming alcohol while taking Isoniazid, as it can increase the risk of liver problems. If you have a history of alcohol abuse, you may also be at higher risk of nerve problems.
Vitamin B6: If you have a history of diabetes, alcohol abuse, or poor nutrition, your doctor may recommend vitamin B6 supplementation to reduce the risk of nerve problems.
Tyramine-Rich Foods: Avoid foods high in tyramine (e.g., aged cheeses, red wines, beer, certain meats and sausages, liver, sour cream, soy sauce, raisins, bananas, avocados) as they can cause severe high blood pressure when combined with Isoniazid. Seek immediate medical attention if you experience symptoms such as severe headache, fast or irregular heartbeat, sore or stiff neck, nausea, vomiting, sweating, enlarged pupils, or sensitivity to light.
Histamine-Rich Foods: Avoid foods high in histamine (e.g., skipjack, tuna, tropical fish) as they can cause low blood pressure, irregular heartbeat, headache, sweating, or flushing. Contact your doctor immediately if any of these symptoms occur.
Viral Infections: Isoniazid is effective only against TB bacteria and does not treat viral infections (e.g., the common cold).
Full Course of Treatment: Complete the full course of Isoniazid treatment to eradicate the infection completely and prevent the development of antibiotic resistance.
Diabetes Patients: Isoniazid may affect blood sugar levels. Monitor your blood sugar closely and consult your doctor before changing your diabetes medication. You may also be at increased risk of nerve problems.
Lab Tests: Regular lab tests, including liver function and eye exams, may be performed to monitor your condition and detect any side effects.
Risk Groups: Black and Hispanic women and patients older than 35 years may have a greater risk of severe liver problems from Isoniazid. Use with caution.
Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, discuss the benefits and risks of using Isoniazid with your doctor. Isoniazid is found in breast milk, so consider potential risks to your baby.

Isoniazid Storage Instructions

Proper storage is crucial to maintain the efficacy of Isoniazid:

Store Isoniazid at room temperature between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted.
Keep away from heat, moisture, and light.
Do not store in the bathroom.
Keep out of reach of children and pets.

Possible Side Effects of Isoniazid

Like all medications, Isoniazid can cause side effects. While many people experience no or only minor side effects, it is important to be aware of potential reactions.

Common Side Effects:

Consult your doctor if any of these common side effects persist or become bothersome:

Mild stomach upset

Severe Side Effects:

Seek immediate medical attention if any of these severe side effects occur:

Severe allergic reactions (rash, hives, itching, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue)
Changes in vision
Chills or fever
Dark urine
General feeling of discomfort
Increased thirst or urination
Joint pain or swelling
Loss of appetite
Memory problems
Mental or mood changes
Nausea
Seizures
Stomach pain or tenderness
Symptoms of low vitamin B6 levels (e.g., confusion, cracks in the corners of the mouth, irritability, mouth redness or soreness, scaly rash)
Tingling or numbness in the hands or feet
Unusual bruising or bleeding
Unusual tiredness or weakness
Vomiting
Yellowing of the skin or eyes

This list may not be exhaustive. If you have any questions or concerns about side effects, contact your healthcare provider.

Isoniazid: Frequently Asked Questions (FAQ)

What is Isoniazid used for?
Isoniazid is used to treat and prevent tuberculosis (TB) and can be used in the treatment of a BCG-oma.
How should I take Isoniazid?
Take Isoniazid exactly as prescribed by your doctor, usually on an empty stomach with a full glass of water. Do not miss any doses and complete the full course of treatment.
What should I avoid while taking Isoniazid?
Avoid alcohol and foods high in tyramine and histamine. Check with your doctor for a complete list of foods to avoid.
What are the common side effects of Isoniazid?
Common side effects include mild stomach upset. Serious side effects require immediate medical attention.
Can I take Isoniazid if I am pregnant or breastfeeding?
Discuss the benefits and risks of using Isoniazid with your doctor if you are pregnant or breastfeeding.