Jutagilin (other name Eldepryl)

Dementias

Jutagilin (other name Eldepryl) 5mg

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90 pills	$0.72	~~$70~~ -7% Only $65
60 pills	$0.77	Only $46

Eldepryl: Comprehensive Medication Guide for Parkinson's Disease Management

Common Use:

Eldepryl (selegiline) is a potent monoamine oxidase inhibitor (MAOI) primarily prescribed to manage the symptoms of Parkinson's disease, a progressive neurological condition impacting movement. Parkinson's disease arises from a deficiency of dopamine, a crucial neurotransmitter responsible for motor control, within specific brain regions. This dopamine depletion leads to motor impairments, including tremors, rigidity, bradykinesia (slowness of movement), and postural instability.

Eldepryl functions by selectively inhibiting monoamine oxidase type B (MAO-B), an enzyme responsible for breaking down dopamine in the brain. By blocking MAO-B, Eldepryl effectively increases dopamine levels in the brain, thereby alleviating motor symptoms associated with Parkinson's disease. It's important to note that Eldepryl is typically used as an adjunct to levodopa/carbidopa, the gold standard treatment for Parkinson's disease, to enhance its effectiveness and potentially reduce the required dosage of levodopa. Eldepryl itself doesn't possess anti-Parkinson effects but complements levodopa therapy.

Dosage and Administration:

Eldepryl is administered orally, typically once or twice daily. Follow these guidelines for optimal usage:

Timing: Take Eldepryl as directed by your physician, usually after breakfast and lunch.
Orally Disintegrating Tablets: If prescribed orally disintegrating tablets, allow them to dissolve completely on your tongue without chewing or swallowing. Refrain from eating or drinking for at least 5 minutes after administration.
Dosage: The standard adult dose is 10 mg per day, divided into two 5 mg doses. However, dosage adjustments may be necessary based on individual patient response and tolerability.
Physician Consultation: Consulting your doctor before starting Eldepryl is crucial to determine the appropriate dosage and to discuss potential risks and benefits. Regular follow-up appointments are essential to monitor treatment efficacy and adjust the dosage if needed.

Important Precautions:

Before initiating Eldepryl therapy, consider the following precautions:

Tyramine-Rich Foods: Avoid consuming foods high in tyramine, an amino acid that can interact with MAOIs and cause a hypertensive crisis (dangerously high blood pressure). These foods include:
- Aged cheeses (e.g., cheddar, brie, blue cheese)
- Cured or processed meats (e.g., salami, pepperoni, bacon)
- Fermented foods (e.g., sauerkraut, kimchi)
- Soy sauce and other soy products
- Tap beer and unpasteurized beer
- Yeast extracts
Medical Conditions: Inform your doctor if you have any of the following conditions:
- Peptic ulcers or duodenal ulcers
- Labile hypertension (unstable blood pressure)
- Cardiac arrhythmias (irregular heartbeats)
- Severe angina pectoris (chest pain)
- Severe liver or kidney dysfunction
- Psychosis or other mental health disorders
Orthostatic Hypotension: Eldepryl can cause orthostatic hypotension (a sudden drop in blood pressure upon standing), leading to dizziness or lightheadedness. Rise slowly from a lying or sitting position to minimize this effect.
Pregnancy and Breastfeeding: Eldepryl's safety during pregnancy and breastfeeding is not fully established. Consult your doctor before using Eldepryl if you are pregnant, planning to become pregnant, or breastfeeding.

Contraindications:

Eldepryl is contraindicated (should not be used) in the following situations:

Hypersensitivity to selegiline or any other ingredients in the formulation.
Concurrent use with meperidine (Demerol) or other narcotic analgesics.
Use of other MAO inhibitors within the past 14 days, including isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), rasagiline (Azilect), and transdermal selegiline (Emsam).
Concomitant use with certain medications, such as:
- Meperidine, propoxyphene, or tramadol
- Methadone
- Cough or cold medicines containing dextromethorphan

Potential Side Effects:

Eldepryl, like all medications, can cause side effects. Not everyone experiences these side effects, and their severity can vary. Common side effects may include:

Serious Side Effects (seek immediate medical attention):
- Signs of an allergic reaction (rash, hives, itching, swelling, difficulty breathing)
- Sudden and severe headache
- Blurred vision
- Nausea, vomiting
- Speech or balance problems
- Seizure
- Chest pain
- Sudden numbness or weakness
- Hallucinations
- Feeling restless, agitated, or irritable
- Twitching muscle movements
- Painful or difficult urination
Less Serious Side Effects (consult your doctor if they persist or worsen):
- Dizziness
- Weakness
- Sleep problems (insomnia)
- Runny or stuffy nose
- Back pain
- Constipation

Drug Interactions:

Eldepryl can interact with several medications. Inform your doctor about all prescription, over-the-counter, and herbal medications you are taking to prevent potential drug interactions. Significant interactions may occur with:

Diet pills or cold medicines containing ephedrine, pseudoephedrine, or phenylephrine.
Carbamazepine (Tegretol).
Nafcillin.
Rifampin (Rifadin).
Antidepressants, including:
- Selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil), and sertraline (Zoloft)
- Serotonin-norepinephrine reuptake inhibitors (SNRIs) such as duloxetine (Cymbalta) and venlafaxine (Effexor)
- Tricyclic antidepressants (TCAs) such as amitriptyline (Elavil), desipramine (Norpramin), and nortriptyline (Pamelor)
- Monoamine oxidase inhibitors (MAOIs) (see Contraindications section)
Phenobarbital.

Missed Dose:

If you miss a dose of Eldepryl, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

Overdose:

Symptoms of an Eldepryl overdose may include severe headache, vision problems, sweating, hallucinations, lightheadedness, cool or clammy skin, fast or uneven heartbeat, fainting, or seizure. Seek immediate medical attention if you suspect an overdose.

Storage:

Store Eldepryl at room temperature between 20-25°C (68-77°F), away from moisture and direct sunlight. Keep out of reach of children.

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FAQ About Eldepryl:

What is Eldepryl used for?
Eldepryl is used to treat the symptoms of Parkinson's disease by increasing dopamine levels in the brain.
How should I take Eldepryl?
Take Eldepryl as directed by your doctor, usually after breakfast and lunch. If you are taking orally disintegrating tablets, allow them to dissolve completely on your tongue.
What foods should I avoid while taking Eldepryl?
Avoid foods high in tyramine, such as aged cheeses, cured meats, and fermented foods, as they can interact with Eldepryl and cause a dangerous increase in blood pressure.
What are the potential side effects of Eldepryl?
Common side effects include dizziness, insomnia, and constipation. Serious side effects can include allergic reactions, hallucinations, and chest pain. Seek medical attention immediately if you experience any serious side effects.
Can I take Eldepryl with other medications?
Eldepryl can interact with several medications. Inform your doctor about all medications you are taking before starting Eldepryl.