Merck-glimepiride (other name Amaryl)

Diabetes

Merck-glimepiride (other name Amaryl) 4mg

Package	Per Pill	Special Price
360 pills Free Express Delivery	$1.18	~~$684~~ -39% Only $424
270 pills Free Express Delivery	$1.20	~~$513~~ -38% Only $323
180 pills Free Regular Delivery	$1.24	~~$342~~ -35% Only $223
120 pills	$1.31	~~$228~~ -32% Only $157
90 pills	$1.37	~~$171~~ -29% Only $123
60 pills	$1.50	~~$114~~ -22% Only $90
30 pills	$1.90	Only $57

Merck-glimepiride (other name Amaryl) 3mg

Package	Per Pill	Special Price
360 pills Free Express Delivery	$1.01	~~$587~~ -39% Only $363
270 pills Free Regular Delivery	$1.03	~~$441~~ -37% Only $278
180 pills	$1.06	~~$294~~ -35% Only $191
120 pills	$1.12	~~$196~~ -32% Only $134
90 pills	$1.18	~~$147~~ -28% Only $106
60 pills	$1.30	~~$98~~ -21% Only $78
30 pills	$1.63	Only $49

Merck-glimepiride (other name Amaryl) 2mg

Package	Per Pill	Special Price
360 pills Free Express Delivery	$0.86	~~$515~~ -40% Only $310
270 pills Free Regular Delivery	$0.87	~~$387~~ -40% Only $235
180 pills	$0.91	~~$258~~ -37% Only $164
120 pills	$0.96	~~$172~~ -33% Only $115
90 pills	$1.01	~~$129~~ -30% Only $91
60 pills	$1.12	~~$86~~ -22% Only $67
30 pills	$1.43	Only $43

Amaryl (Glimepiride): Comprehensive Information for Effective Diabetes Management

What is Amaryl?

Amaryl, containing the active ingredient Glimepiride, is an oral hypoglycemic medication belonging to the sulfonylurea class. It is a prescription drug primarily used to manage type 2 diabetes mellitus (non-insulin dependent diabetes). Amaryl works by stimulating the release of insulin from the beta cells of the pancreas, thereby lowering blood sugar levels. It is typically prescribed alongside a balanced diet and regular exercise to achieve optimal glycemic control.

Therapeutic Uses of Amaryl

Type 2 Diabetes Mellitus: Amaryl is indicated as a monotherapy or in combination with other antidiabetic agents like metformin or insulin to manage blood sugar levels in individuals with type 2 diabetes.
Glycemic Control: It aids in maintaining stable blood glucose levels throughout the day, reducing the risk of hyperglycemia (high blood sugar) and its associated complications.

How Amaryl Works (Mechanism of Action)

Glimepiride, the active component of Amaryl, exerts its hypoglycemic effect through the following mechanisms:

Insulin Secretagogue: It stimulates the pancreatic beta cells to release more insulin.
Increased Insulin Sensitivity: It may also enhance the sensitivity of peripheral tissues to insulin, improving glucose uptake and utilization.

Amaryl Dosage and Administration

The dosage of Amaryl is individualized based on the patient's blood glucose levels, HbA1c, and overall response to treatment. It's important to strictly adhere to the prescription given by your healthcare provider. The medication is usually taken once daily, preferably before breakfast or the first main meal.

Starting Dose: Typically, the initial dose is 1 mg once daily.
Dosage Adjustments: Your doctor may gradually increase the dosage based on your glycemic response, usually at intervals of 1-2 weeks.
Maximum Daily Dose: The maximum recommended daily dose is 8 mg.

Important Precautions While Using Amaryl

Hypoglycemia Awareness: Be aware of the signs and symptoms of hypoglycemia (low blood sugar), which may include sweating, shakiness, dizziness, hunger, confusion, and rapid heartbeat. Always carry a source of quick-acting glucose (e.g., glucose tablets, fruit juice) to treat hypoglycemia.
Regular Blood Glucose Monitoring: Monitor your blood glucose levels regularly as directed by your physician. Keep a record of your readings and share them with your healthcare provider during check-ups.
Medical Conditions and Medications: Inform your doctor about all existing medical conditions and any medications you are currently taking, including over-the-counter drugs and herbal supplements, to prevent potential drug interactions.
Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding before using Amaryl, as it may not be safe for the fetus or infant.
Alcohol Consumption: Limit or avoid alcohol consumption while taking Amaryl, as it can increase the risk of hypoglycemia.
Driving and Operating Machinery: Exercise caution when driving or operating machinery, as Amaryl can cause hypoglycemia, which may impair your ability to perform these tasks safely.
Illness and Surgery: Inform your doctor if you are ill or undergoing surgery, as your diabetes management plan may need to be adjusted temporarily.

Contraindications – When Amaryl Should Not Be Used

Amaryl is contraindicated in the following conditions:

Type 1 diabetes mellitus
Diabetic ketoacidosis
Severe renal or hepatic impairment
Known hypersensitivity to glimepiride, other sulfonylureas, or sulfonamides

Potential Side Effects of Amaryl

Like all medications, Amaryl can cause side effects, although not everyone experiences them. Common side effects may include:

Hypoglycemia (low blood sugar)
Nausea
Vomiting
Diarrhea
Headache
Dizziness
Weight gain

Serious side effects are rare but may include:

Allergic reactions (rash, itching, hives, swelling)
Liver problems (jaundice, dark urine, abdominal pain)
Blood disorders (anemia, leukopenia, thrombocytopenia)

Seek immediate medical attention if you experience any serious side effects.

Amaryl Interactions with Other Medications

Amaryl can interact with various medications, potentially affecting its efficacy or increasing the risk of side effects. It is essential to inform your doctor about all medications you are taking. Significant drug interactions may occur with:

Other antidiabetic drugs (e.g., insulin, metformin)
Nonsteroidal anti-inflammatory drugs (NSAIDs)
Salicylates (e.g., aspirin)
Sulfonamides
Beta-blockers (e.g., propranolol, atenolol)
ACE inhibitors (e.g., enalapril, lisinopril)
MAO inhibitors (e.g., phenelzine, tranylcypromine)
Certain antifungal medications (e.g. fluconazole)
Corticosteroids (e.g., prednisone)
Diuretics (e.g., hydrochlorothiazide)
Thyroid medications
Anticoagulants (e.g., warfarin)

What to Do in Case of a Missed Dose

If you miss a dose of Amaryl, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for the missed one.

Managing an Amaryl Overdose

An overdose of Amaryl can lead to severe hypoglycemia. Symptoms of overdose may include:

Confusion
Sweating
Shakiness
Loss of consciousness
Seizures

If you suspect an overdose, seek immediate medical attention.

Proper Storage of Amaryl

Store Amaryl tablets at room temperature, away from light, heat, and moisture. Keep the medication out of reach of children and pets.

Where to Buy Amaryl Online

Amaryl is available for purchase at most pharmacies, with a prescription from a medical doctor. Also, you can buy Amaryl online from reputable online pharmacies. Ensure that the online pharmacy requires a valid prescription and is properly licensed and regulated.

Amaryl: Affordable Prices and Discounts

Find Amaryl at competitive prices at your local pharmacy or online. Look out for discounts and promotions to save on your prescription costs.

Frequently Asked Questions (FAQ) about Amaryl

Q: What is Amaryl used for?
A: Amaryl is used to treat type 2 diabetes mellitus by helping to lower blood sugar levels.

Q: How should I take Amaryl?
A: Take Amaryl exactly as prescribed by your doctor, usually once daily before breakfast or the first main meal.

Q: What should I do if I experience hypoglycemia while taking Amaryl?
A: Treat hypoglycemia immediately by consuming a source of quick-acting glucose, such as glucose tablets or fruit juice. Monitor your blood sugar levels and consult your doctor.

Q: Can I drink alcohol while taking Amaryl?
A: It is recommended to limit or avoid alcohol consumption while taking Amaryl, as it can increase the risk of hypoglycemia.

Q: What are the common side effects of Amaryl?
A: Common side effects may include hypoglycemia, nausea, vomiting, diarrhea, and headache.

Q: Is Amaryl safe to use during pregnancy or breastfeeding?
A: Consult your doctor before using Amaryl if you are pregnant, planning to become pregnant, or breastfeeding.

Q: How do I store Amaryl?
A: Store Amaryl tablets at room temperature, away from light, heat, and moisture. Keep the medication out of reach of children and pets.

Disclaimer: This information is intended for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.