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Pyramistin (other name Artane)

Pyramistin (other name Artane) 2mg

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Artane (Trihexyphenidyl) - Product Information

Artane, containing trihexyphenidyl hydrochloride, is a medication used to manage symptoms of Parkinson's disease and control extrapyramidal disorders caused by certain medications. It works by altering nerve impulses and relaxing stiff muscles, helping to improve movement and reduce rigidity.

Common Uses of Artane

  • Management of Parkinson's disease symptoms (tremors, rigidity, slow movement)
  • Control of extrapyramidal symptoms caused by medications like antipsychotics

Dosage and Administration

Always take Artane exactly as prescribed by your healthcare provider. The dosage is individualized based on your condition and response to treatment.

  1. Take each dose with a full glass of water.
  2. Artane can be taken with or without meals. Taking it with food may reduce stomach upset.
  3. Use a dose-measuring spoon or cup for liquid formulations to ensure accurate dosing.
  4. Dosage adjustments may be necessary, especially for patients over 60 years of age.
  5. The timing of administration (before or after meals) should be determined based on individual patient response, particularly regarding saliva production and potential nausea.

Important Considerations:

  • Do not abruptly stop taking Artane, as this may lead to a worsening of Parkinson's symptoms or neuroleptic malignant syndrome (NMS).
  • If a dose is missed, take it as soon as you remember, unless it's almost time for the next dose. Do not double the dose.

Contraindications and Precautions

Before taking Artane, inform your doctor about any allergies, medical conditions, and medications you are currently taking. This medication should not be used if you have:

  • Known allergy to trihexyphenidyl
  • Narrow-angle glaucoma
  • Blockage of the bladder, esophagus, stomach, or intestines
  • Severe ulcerative colitis

Exercise caution and consult with your doctor if you have:

  • Alcohol use
  • Breathing problems (asthma, emphysema)
  • Diarrhea caused by infection
  • Enlarged prostate or difficulty urinating
  • Epilepsy or seizure disorder
  • Heart disease or irregular heartbeat
  • Depression or other psychiatric illness
  • Kidney or liver disease

Drug Interactions

Inform your healthcare provider of all medications, supplements, and herbal products you are taking to avoid potential drug interactions.

Pregnancy and Breastfeeding

Consult with your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking Artane. The potential risks and benefits should be discussed.

Storage Information

  • Store Artane at room temperature (68-77°F or 20-25°C).
  • Keep away from heat, moisture, and light.
  • Store in a tight, light-resistant container.
  • Keep out of reach of children and pets.

Safety Information

Patients with cardiac, liver, or kidney disorders, or with hypertension, should be closely monitored while taking Artane. Because Artane has atropine-like properties, long-term treatment requires careful monitoring for adverse reactions. It should be used with caution in patients with glaucoma, obstructive disease of the gastrointestinal or genitourinary tracts, and in elderly males with possible prostatic hypertrophy. Regular eye exams are recommended.

Possible Side Effects of Artane

Common Side Effects:

  • Dryness of the mouth
  • Blurred vision
  • Dizziness
  • Mild nausea
  • Nervousness
  • Constipation
  • Decreased Sweating

These side effects are usually mild and may decrease over time. Consult your doctor if they become bothersome.

Serious Side Effects (Seek Immediate Medical Attention):

  • Allergic reaction (difficulty breathing, swelling, hives)
  • Fever
  • Fast or irregular heartbeats
  • Anxiety, hallucinations, confusion, agitation, hyperactivity, or loss of consciousness
  • Seizures
  • Eye pain
  • Rash

This is not an exhaustive list of side effects. Report any unusual symptoms to your doctor.

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Artane FAQ

Q: What is Artane used for?

A: Artane is used to treat symptoms of Parkinson's disease and control extrapyramidal disorders.

Q: How should I take Artane?

A: Take Artane exactly as prescribed by your doctor, usually with a full glass of water. It can be taken with or without food.

Q: What should I do if I miss a dose?

A: Take the missed dose as soon as you remember, unless it's almost time for your next dose. Do not double the dose.

Q: What are the common side effects of Artane?

A: Common side effects include dry mouth, blurred vision, and dizziness.

Q: Can I stop taking Artane abruptly?

A: No, do not stop taking Artane abruptly without consulting your doctor, as it may worsen your symptoms.

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