Zylol (other name Allopurinol)

Gastrointestinal Tract

Zylol (other name Allopurinol) 300mg

Package	Per Pill	Special Price
360 pills Free Regular Delivery	$0.66	~~$314~~ -25% Only $238
270 pills	$0.67	~~$235~~ -23% Only $182
180 pills	$0.70	~~$157~~ -20% Only $126
120 pills	$0.74	~~$105~~ -15% Only $89
90 pills	$0.79	~~$79~~ -10% Only $71
60 pills	$0.87	Only $52

Allopurinol: Your Comprehensive Guide to Gout and Hyperuricemia Treatment

Buy Allopurinol online for effective management of gout and related conditions. Allopurinol is a trusted medication that works by reducing the production of uric acid in the body. It's a vital treatment option for individuals seeking relief from the pain and discomfort of gout, as well as for those managing hyperuricemia.

What is Allopurinol and How Does It Work?

Allopurinol belongs to a class of drugs known as xanthine oxidase inhibitors. Its primary function is to block the action of xanthine oxidase, an enzyme responsible for converting hypoxanthine to xanthine and then to uric acid. By inhibiting this enzyme, Allopurinol effectively lowers uric acid levels in the blood and urine. This is crucial in preventing the formation of uric acid crystals, which are the root cause of gout and kidney stones related to urates.

Key Benefits of Allopurinol

Gout Treatment: Allopurinol is a cornerstone medication for managing gout, reducing the frequency and severity of gout attacks.
Hyperuricemia Management: It helps control abnormally high levels of uric acid in the blood, preventing complications like kidney damage and tophi formation.
Kidney Stone Prevention: By lowering uric acid levels, Allopurinol reduces the risk of urate kidney stones.
Prophylaxis in Cancer Treatment: It's used to prevent hyperuricemia in patients undergoing chemotherapy or radiation therapy for certain cancers.

Uses of Allopurinol

Allopurinol is primarily prescribed for the following conditions:

Primary and Secondary Gout: Management of gout caused by genetic factors or other underlying conditions.
Nephrolithiasis (Urate Kidney Stones): Prevention of kidney stone formation due to high uric acid levels.
Hyperuricemia: Treatment of high uric acid levels resulting from various causes, including leukemia and other conditions involving rapid cell turnover.
Tumor Lysis Syndrome: Prevention of hyperuricemia associated with the breakdown of cancer cells during treatment.

Dosage and Administration

The dosage of Allopurinol varies depending on the individual's condition and uric acid levels. A typical starting dose is 100 mg per day, which may be gradually increased to 300-800 mg per day as needed. For acute gout and tophi, a daily dose of 300-400 mg is often prescribed. Doses exceeding 300 mg should be divided into multiple administrations throughout the day.

Important Considerations:

Take Allopurinol with food to minimize stomach irritation.
Avoid taking large doses of vitamin C, as it may increase the risk of kidney stones.
Drink plenty of water to help flush out uric acid and prevent kidney stone formation.
Limit alcohol consumption and intake of purine-rich foods like sweetbreads, sardines, anchovies, kidneys, liver, and lentils.

Precautions and Warnings

Before taking Allopurinol, inform your doctor about any existing medical conditions, especially:

Kidney dysfunction
Diabetes
Liver disease
Heart failure
Hypertension

Allopurinol treatment may require several months to show significant improvement in symptoms. Regular intake is crucial, even if immediate effects are not apparent. Some individuals may experience acute gout attacks more frequently at the beginning of treatment. These attacks should become shorter and less severe as therapy progresses.

Stop taking Allopurinol immediately and consult your doctor if you experience any signs of an allergic reaction, such as rash, itching, facial swelling, or difficulty breathing. Severe skin reactions, liver damage, and inflammation of blood vessels are possible, though rare.

Contraindications

Allopurinol is contraindicated in the following conditions:

Hypersensitivity to Allopurinol
Severe hepatic or renal disorders
Primary hemochromatosis
Asymptomatic hyperuricemia
Acute gout attacks
Pregnancy and lactation
Children under 14 years (unless for specific conditions like leukemia or malignant tumors)

Possible Side Effects

Common side effects of Allopurinol may include:

Diarrhea
Nausea
Skin rash or itching
Drowsiness

Seek immediate medical attention if you experience any of the following serious side effects:

Severe skin rash or blistering
Painful or bloody urination
Eye irritation
Facial swelling
Loss of appetite
Jaundice (yellowing of the skin or eyes)

Rarely, Allopurinol can cause nerve damage, kidney damage, or bone marrow suppression. Liver toxicity is also a possibility, especially in patients with kidney impairment.

Drug Interactions

Allopurinol can interact with several medications. Inform your doctor about all medications you are taking, including:

Mercaptopurine (Purinethol) and azathioprine (Imuran): Allopurinol can increase the blood levels of these medications, requiring dose adjustments.
Penicillins: The risk of skin rash may increase when taking Allopurinol with penicillins.
Warfarin: Allopurinol may increase the effect of Warfarin and increase bleeding risk.

Missed Dose

If you miss a dose of Allopurinol, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

Overdose

In case of suspected Allopurinol overdose, seek immediate medical attention. While specific information on Allopurinol overdose is limited, supportive care and symptomatic treatment are essential.

Storage

Store Allopurinol at room temperature, below 25°C (77°F), away from moisture, heat, and direct sunlight. Keep out of reach of children and pets.

Where to Buy Allopurinol Online

You can order Allopurinol online from our trusted pharmacy. We offer competitive Allopurinol prices and ensure the authenticity and quality of our medications. Get your Allopurinol prescription filled conveniently and discreetly.

FAQ About Allopurinol

What is the price of Allopurinol? The price of Allopurinol varies depending on the dosage and quantity. Check our website for the most up-to-date pricing.
Can I buy Allopurinol without a prescription? No, Allopurinol is a prescription medication. You will need a valid prescription from a healthcare provider to purchase it.
How long does Allopurinol take to work? It may take several weeks to months for Allopurinol to reach its full effect. It's important to continue taking the medication as prescribed, even if you don't see immediate results.
What are the alternatives to Allopurinol? Other medications used to treat gout and hyperuricemia include febuxostat and probenecid. Discuss alternative treatment options with your doctor.
Can I drink alcohol while taking Allopurinol? It's recommended to limit alcohol consumption while taking Allopurinol, as alcohol can raise uric acid levels and interfere with the medication's effectiveness.

Disclaimer: This information is for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment. We disclaim any liability for the accuracy or completeness of this information and for any consequences arising from its use.